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Ezetimibe Benzyl Diol Impurity

SZ CAT No SZ-E026006
CAS No 1374250-06-2
Mol.F. C31H31F2NO3
Mol.Wt. 503.6
Inv. Status Custom Synthesis


Chemical Name: (1S,4R)-4-((S)-(4-(Benzyloxy)phenyl)((4-fluorophenyl)amino)methyl)-1-(4-fluorophenyl)pentane-1,5-diol

Smiles: O[C@@H](CC[C@H]([C@@H](C1=CC=C(OCC2=CC=CC=C2)C=C1)NC3=CC=C(F)C=C3)CO)C4=CC=C(F)C=C4

Inchi: InChI=1S/C24H21F2NO3.H2O/c25-17-8-4-15(5-9-17)22(29)13-12-21-23(16-6-10-20(28)11-7-16)27(24(21)30)19-3-1-2-18(26)14-19;/h1-11,14,21-23,28-29H,12-13H2;1H2/t21-,22+,23-;/m1./s1

Related substances by HPLC method for the detection and evaluation of impurities in ezetimibe drug material
By Rapeti, Durgababu; Reddy, Gudibanda Chandra Sekhar; Narayanarao, Kapavarapu Maruthi Venkata; Shyamala, Pulipaka; Krishna, Rallabhandi Murali
From International Journal of Pharmaceutical Sciences and Research (2021), 12(1), 217-225
 
Stability-​indicating liquid chromatographic method for the simultaneous determination of rosuvastatin and ezetimibe from pharmaceuticals and biological samples
By Kurbanoglu, Sevinc; Esim, Ozgur; Ozkan, Cansel Kose; Savaser, Ayhan; Ozkan, Yalcin; Uslu, Bengi; Ozkan, Sibel A.
From Journal of the Turkish Chemical Society, Section A: Chemistry (2020), 7(3), 865-874
 
Stability-​indicating analytical method development using quality by design approach for simultaneous estimation of ezetimibe and glimepiride
By Shah, U.; Shah, Kunti; Patel, Rupal
From Indian Journal of Pharmaceutical Sciences (2019), 81(2), 273-281