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Ezetimibe Diacetate

SZ CAT No SZ-E026043
CAS No 163222-39-7
Mol.F. C28H25F2NO5
Mol.Wt. 493.5
Inv. Status Custom Synthesis


Chemical Name: 4-((2S,3R)-3-((R)-3-Acetoxy-3-(4-fluorophenyl)propyl)-1-(4-fluorophenyl)-4-oxoazetidin-2-yl)phenyl acetate

Smiles: O=C1[C@H](CC[C@H](C2=CC=C(F)C=C2)OC(C)=O)[C@@H](C3=CC=C(OC(C)=O)C=C3)N1C4=CC=C(F)C=C4

Inchi: InChI=1S/C24H22FNO3/c25-18-10-6-16(7-11-18)22(28)15-14-21-23(17-8-12-20(27)13-9-17)26(24(21)29)19-4-2-1-3-5-19/h1-13,21-23,27-28H,14-15H2/t21-,22+,23-/m1/s1

Related substances by HPLC method for the detection and evaluation of impurities in ezetimibe drug material
By Rapeti, Durgababu; Reddy, Gudibanda Chandra Sekhar; Narayanarao, Kapavarapu Maruthi Venkata; Shyamala, Pulipaka; Krishna, Rallabhandi Murali
From International Journal of Pharmaceutical Sciences and Research (2021), 12(1), 217-225
 
Stability-​indicating liquid chromatographic method for the simultaneous determination of rosuvastatin and ezetimibe from pharmaceuticals and biological samples
By Kurbanoglu, Sevinc; Esim, Ozgur; Ozkan, Cansel Kose; Savaser, Ayhan; Ozkan, Yalcin; Uslu, Bengi; Ozkan, Sibel A.
From Journal of the Turkish Chemical Society, Section A: Chemistry (2020), 7(3), 865-874
 
Stability-​indicating analytical method development using quality by design approach for simultaneous estimation of ezetimibe and glimepiride
By Shah, U.; Shah, Kunti; Patel, Rupal
From Indian Journal of Pharmaceutical Sciences (2019), 81(2), 273-281