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Racemic Ezetimibe D4

SZ CAT No SZ-E026D01
CAS No NA
Mol.F. C24H17D4F2NO3
Mol.Wt. 413.5
Inv. Status Custom Synthesis


Chemical Name: (3R,4S)-1-(4-Fluorophenyl)-3-(3-(4-fluorophenyl-2,3,5,6-d4)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one

Smiles: OC(C=C1)=CC=C1[C@H]2N(C3=CC=C(F)C=C3)C([C@@H]2CCC(O)C4=C([2H])C([2H])=C(F)C([2H])=C4[2H])=O

Inchi: InChI=1S/C19H26O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h11,14-16H,3-10H2,1-2H3/t14-,15-,16-,18-,19-/m0/s1/i3D2,6D2,7D2,11D

Related substances by HPLC method for the detection and evaluation of impurities in ezetimibe drug material
By Rapeti, Durgababu; Reddy, Gudibanda Chandra Sekhar; Narayanarao, Kapavarapu Maruthi Venkata; Shyamala, Pulipaka; Krishna, Rallabhandi Murali
From International Journal of Pharmaceutical Sciences and Research (2021), 12(1), 217-225
 
Stability-​indicating liquid chromatographic method for the simultaneous determination of rosuvastatin and ezetimibe from pharmaceuticals and biological samples
By Kurbanoglu, Sevinc; Esim, Ozgur; Ozkan, Cansel Kose; Savaser, Ayhan; Ozkan, Yalcin; Uslu, Bengi; Ozkan, Sibel A.
From Journal of the Turkish Chemical Society, Section A: Chemistry (2020), 7(3), 865-874
 
Stability-​indicating analytical method development using quality by design approach for simultaneous estimation of ezetimibe and glimepiride
By Shah, U.; Shah, Kunti; Patel, Rupal
From Indian Journal of Pharmaceutical Sciences (2019), 81(2), 273-281