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Ezetimibe Impurity 17

SZ CAT No SZ-E026067
CAS No 1251741-03-3
Mol.F. C24H23NO3
Mol.Wt. 373.5
Inv. Status Custom Synthesis


Chemical Name: (3R,4S)-3-((S)-3-Hydroxy-3-phenylpropyl)-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one

Smiles: O[C@@H](CC[C@H]1C(N(C2=CC=CC=C2)[C@@H]1C3=CC=C(O)C=C3)=O)C4=CC=CC=C4

Inchi: InChI=1S/C33H30F2N2O5/c34-24-10-6-22(7-11-24)30(39)19-18-28(32(40)37-29(20-42-33(37)41)21-4-2-1-3-5-21)31(23-8-16-27(38)17-9-23)36-26-14-12-25(35)13-15-26/h1-17,28-31,36,38-39H,18-20H2/t28-,29+,30+,31-/m0/s1

Related substances by HPLC method for the detection and evaluation of impurities in ezetimibe drug material
By Rapeti, Durgababu; Reddy, Gudibanda Chandra Sekhar; Narayanarao, Kapavarapu Maruthi Venkata; Shyamala, Pulipaka; Krishna, Rallabhandi Murali
From International Journal of Pharmaceutical Sciences and Research (2021), 12(1), 217-225
 
Stability-​indicating liquid chromatographic method for the simultaneous determination of rosuvastatin and ezetimibe from pharmaceuticals and biological samples
By Kurbanoglu, Sevinc; Esim, Ozgur; Ozkan, Cansel Kose; Savaser, Ayhan; Ozkan, Yalcin; Uslu, Bengi; Ozkan, Sibel A.
From Journal of the Turkish Chemical Society, Section A: Chemistry (2020), 7(3), 865-874
 
Stability-​indicating analytical method development using quality by design approach for simultaneous estimation of ezetimibe and glimepiride
By Shah, U.; Shah, Kunti; Patel, Rupal
From Indian Journal of Pharmaceutical Sciences (2019), 81(2), 273-281