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Ezetimibe Impurity 12

SZ CAT No SZ-E026062
CAS No NA
Mol.F. C24H21F2NO3
Mol.Wt. 409.4
Inv. Status Custom Synthesis


Chemical Name: (3R,4S)-1-(3-Fluorophenyl)-3-((S)-3-(3-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one

Smiles: FC1=CC([C@@H](O)CC[C@H]2C(N(C3=CC=CC(F)=C3)[C@@H]2C4=CC=C(O)C=C4)=O)=CC=C1

Inchi: InChI=1S/C24H21F2NO3/c25-17-9-5-15(6-10-17)22(29)14-13-19-23(16-7-11-18(28)12-8-16)27(24(19)30)21-4-2-1-3-20(21)26/h1-12,19,22-23,28-29H,13-14H2/t19-,22+,23-/m1/s1

Related substances by HPLC method for the detection and evaluation of impurities in ezetimibe drug material
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From International Journal of Pharmaceutical Sciences and Research (2021), 12(1), 217-225
 
Stability-​indicating liquid chromatographic method for the simultaneous determination of rosuvastatin and ezetimibe from pharmaceuticals and biological samples
By Kurbanoglu, Sevinc; Esim, Ozgur; Ozkan, Cansel Kose; Savaser, Ayhan; Ozkan, Yalcin; Uslu, Bengi; Ozkan, Sibel A.
From Journal of the Turkish Chemical Society, Section A: Chemistry (2020), 7(3), 865-874
 
Stability-​indicating analytical method development using quality by design approach for simultaneous estimation of ezetimibe and glimepiride
By Shah, U.; Shah, Kunti; Patel, Rupal
From Indian Journal of Pharmaceutical Sciences (2019), 81(2), 273-281