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Ezetimibe Impurity 33

SZ CAT No SZ-E026085
CAS No NA
Mol.F. C24H21F2NO3
Mol.Wt. 409.4
Inv. Status Custom Synthesis


Chemical Name: (3R,4R)-1-(4-Fluorophenyl)-4-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-3-(4-hydroxyphenyl)azetidin-2-one

Smiles: O=C1N(C2=CC=C(F)C=C2)[C@H](CC[C@@H](C3=CC=C(F)C=C3)O)[C@H]1C4=CC=C(O)C=C4

Inchi: InChI=1/C27H35BN4O4/c1-5-23(28-35-22-15-18-14-21(26(18,2)3)27(22,4)36-28)32-24(33)19(13-17-9-7-6-8-10-17)31-25(34)20-16-29-11-12-30-20/h6-12,16,18-19,21-23H,5,13-15H2,1-4H3,(H,31,34)(H,32,33)

Related substances by HPLC method for the detection and evaluation of impurities in ezetimibe drug material
By Rapeti, Durgababu; Reddy, Gudibanda Chandra Sekhar; Narayanarao, Kapavarapu Maruthi Venkata; Shyamala, Pulipaka; Krishna, Rallabhandi Murali
From International Journal of Pharmaceutical Sciences and Research (2021), 12(1), 217-225
 
Stability-​indicating liquid chromatographic method for the simultaneous determination of rosuvastatin and ezetimibe from pharmaceuticals and biological samples
By Kurbanoglu, Sevinc; Esim, Ozgur; Ozkan, Cansel Kose; Savaser, Ayhan; Ozkan, Yalcin; Uslu, Bengi; Ozkan, Sibel A.
From Journal of the Turkish Chemical Society, Section A: Chemistry (2020), 7(3), 865-874
 
Stability-​indicating analytical method development using quality by design approach for simultaneous estimation of ezetimibe and glimepiride
By Shah, U.; Shah, Kunti; Patel, Rupal
From Indian Journal of Pharmaceutical Sciences (2019), 81(2), 273-281