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Ezetimibe Isomer

SZ CAT No SZ-E026079
CAS No NA
Mol.F. C44H52F2N2O6Si
Mol.Wt. 771.0
Inv. Status Out of Stock


Chemical Name: (S)-3-((R)-2-((R)-(4-((Tert-butyldimethylsilyl)oxy)phenyl)((4-fluorophenyl)amino)methyl)-4-(2-(4-fluorophenyl)-5,5-dimethyl-1,3-dioxan-2-yl)butanoyl)-4-phenyloxazolidin-2-one

Smiles: O=C(N1[C@@H](C2=CC=CC=C2)COC1=O)[C@H](CCC3(OCC(C)(C)CO3)C4=CC=C(F)C=C4)[C@H](C5=CC=C(O[Si](C)(C)C(C)(C)C)C=C5)NC6=CC=C(F)C=C6

Inchi: InChI=1S/C38H38F2N2O6/c1-37(2)23-47-38(48-24-37,27-10-12-28(39)13-11-27)21-20-32(35(44)42-33(22-46-36(42)45)25-6-4-3-5-7-25)34(26-8-18-31(43)19-9-26)41-30-16-14-29(40)15-17-30/h3-19,32-34,41,43H,20-24H2,1-2H3/t32-,33-,34-/m1/s1

Related substances by HPLC method for the detection and evaluation of impurities in ezetimibe drug material
By Rapeti, Durgababu; Reddy, Gudibanda Chandra Sekhar; Narayanarao, Kapavarapu Maruthi Venkata; Shyamala, Pulipaka; Krishna, Rallabhandi Murali
From International Journal of Pharmaceutical Sciences and Research (2021), 12(1), 217-225
 
Stability-​indicating liquid chromatographic method for the simultaneous determination of rosuvastatin and ezetimibe from pharmaceuticals and biological samples
By Kurbanoglu, Sevinc; Esim, Ozgur; Ozkan, Cansel Kose; Savaser, Ayhan; Ozkan, Yalcin; Uslu, Bengi; Ozkan, Sibel A.
From Journal of the Turkish Chemical Society, Section A: Chemistry (2020), 7(3), 865-874
 
Stability-​indicating analytical method development using quality by design approach for simultaneous estimation of ezetimibe and glimepiride
By Shah, U.; Shah, Kunti; Patel, Rupal
From Indian Journal of Pharmaceutical Sciences (2019), 81(2), 273-281