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Ezetimibe

SZ CAT No SZ-E026001
CAS No 163222-33-1
Mol.F. C24H21F2NO3
Mol.Wt. 409.4
Inv. Status In Stock


Chemical Name: (3R,4S)-1-(4-Fluorophenyl)-3-((S)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one (as per USP)

Synonym: (3'S,3R,4S)-Ezetimibe ; (SRS)-Ezetimibe ; Ezetrol

Smiles: OC(C=C1)=CC=C1[C@H]([C@H](C2=O)CC[C@H](O)C3=CC=C(F)C=C3)N2C4=CC=C(F)C=C4

Inchi: InChI=1S/C11H8N2O6/c1-19-9-4-6(2-7(5-12)11(15)16)3-8(10(9)14)13(17)18/h2-4,14H,1H3,(H,15,16)/b7-2+

Related substances by HPLC method for the detection and evaluation of impurities in ezetimibe drug material
By Rapeti, Durgababu; Reddy, Gudibanda Chandra Sekhar; Narayanarao, Kapavarapu Maruthi Venkata; Shyamala, Pulipaka; Krishna, Rallabhandi Murali
From International Journal of Pharmaceutical Sciences and Research (2021), 12(1), 217-225
 
Stability-​indicating liquid chromatographic method for the simultaneous determination of rosuvastatin and ezetimibe from pharmaceuticals and biological samples
By Kurbanoglu, Sevinc; Esim, Ozgur; Ozkan, Cansel Kose; Savaser, Ayhan; Ozkan, Yalcin; Uslu, Bengi; Ozkan, Sibel A.
From Journal of the Turkish Chemical Society, Section A: Chemistry (2020), 7(3), 865-874
 
Stability-​indicating analytical method development using quality by design approach for simultaneous estimation of ezetimibe and glimepiride
By Shah, U.; Shah, Kunti; Patel, Rupal
From Indian Journal of Pharmaceutical Sciences (2019), 81(2), 273-281