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Ezetimibe Impurity 23

SZ CAT No SZ-E026074
CAS No NA
Mol.F. C24H21F2NO3
Mol.Wt. 409.4
Inv. Status Custom Synthesis


Chemical Name: 1-(4-Fluorophenyl)-3(S)-[3(S)-(4-fluorophenyl)-3-hydroxypropyl]-4(S)-(4-hydroxyphenyl)azetidin-2-one

Smiles: O=C1N(C2=CC=C(F)C=C2)[C@@H](CC[C@@H](C3=CC=C(F)C=C3)O)[C@@H]1C4=CC=C(O)C=C4

Inchi: InChI=1S/C14H18N4O3/c1-8-13(20)12(5-19)10(3-16-8)6-21-7-11-4-17-9(2)18-14(11)15/h3-4,19-20H,5-7H2,1-2H3,(H2,15,17,18)

Related substances by HPLC method for the detection and evaluation of impurities in ezetimibe drug material
By Rapeti, Durgababu; Reddy, Gudibanda Chandra Sekhar; Narayanarao, Kapavarapu Maruthi Venkata; Shyamala, Pulipaka; Krishna, Rallabhandi Murali
From International Journal of Pharmaceutical Sciences and Research (2021), 12(1), 217-225
 
Stability-​indicating liquid chromatographic method for the simultaneous determination of rosuvastatin and ezetimibe from pharmaceuticals and biological samples
By Kurbanoglu, Sevinc; Esim, Ozgur; Ozkan, Cansel Kose; Savaser, Ayhan; Ozkan, Yalcin; Uslu, Bengi; Ozkan, Sibel A.
From Journal of the Turkish Chemical Society, Section A: Chemistry (2020), 7(3), 865-874
 
Stability-​indicating analytical method development using quality by design approach for simultaneous estimation of ezetimibe and glimepiride
By Shah, U.; Shah, Kunti; Patel, Rupal
From Indian Journal of Pharmaceutical Sciences (2019), 81(2), 273-281