All Categories
  • All Categories
  • Accessories
  • Accessories & More
  • Butters & Eggs
  • Camera & Video
  • Mornitors
  • Tablets
  • Laptops
  • Handbags
  • Headphone & Speaker
  • Herbs & botanicals
  • Vegetables
  • Shop
  • Laptops & Desktops
  • Watchs
  • Electronic

Apixaban Methyl Impurity

SZ CAT No SZ-A062076
CAS No 70736-27-5
Mol.F. C10H11ClN2O3
Mol.Wt. 242.7
Inv. Status Custom Synthesis


Chemical Name: Methyl (Z)-2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate

Smiles: COC1=CC=C(N/N=C(Cl)/C(OC)=O)C=C1

Inchi: InChI=1S/C24H25N7O4/c1-13-17-12-27-24(28-18-8-7-16(11-26-18)30-10-9-25-21(33)23(30)35)29-20(17)31(15-5-3-4-6-15)22(34)19(13)14(2)32/h7-8,11-12,15H,3-6,9-10H2,1-2H3,(H,25,33)(H,26,27,28,29)

Evaluation of Crushed Tablet for Oral Administration and the Effect of Food on Apixaban Pharmacokinetics in Healthy Adults
YanSongPhD1MingChangPhD1AkiyukiSuzukiMS2Robert J.A.FrostMD, PhD3AnneKellyPhD4FrankLaCretaPhD3CharlesFrostPharmD
Clinical Therapeutics Volume 38, Issue 7, July 2016, Pages 1674-1685.e1
 
Development and validation of seven phenyl hydrazine chloro ester isomers (pgis) by rp-hplc-uv method in anticoagulant drug substance; apixaban
Saradhi venkata ramana v.a,b*, durga raja k.a,b, raghu babu k.a, padma m.a, jagadeesh kumar v.b, pavan kumar k. s. r.b, hemant kumar sharma
Int J Curr Pharm Res, Vol 12, Issue 2, 119-123
 
Stability-Indicating High-Perform ance Liquid Chrom atographie Determ ination of Apixaban in the Presence of Degradation Products
Swarup Suresh Prabhune *, Rajendra Shankar Jaguste, Prakash Laxman Kondalkar, Nitin Sharadchandra Pradhan
Sei Pharm. 2014; 82: 777-785
 
Analytical Quality by Design Approach for a Stability‑Indicating Method to Determine Apixaban and Its Related Impurities
Jéssica B. Ellwanger1  · Nathalie Ribeiro Wingert1  · Nadia Maria Volpato1  · Cássia Virginia Garcia1  · Elfrides E. S. Schapoval1  · Martin Steppe
Chromatographia volume 83, pages65–75(2020)