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Apixaban Impurity 15

SZ CAT No SZ-A062026
CAS No 1466571-07-2
Mol.F. C21H20N4O4 
Mol.Wt. 392.4
Inv. Status In Stock


Chemical Name: Methyl 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

Smiles: COC(C=C1)=CC=C1N2C3=C(CCN(C4=CC=C(N)C=C4)C3=O)C(C(OC)=O)=N2

Inchi: InChI=1S/C46H57NO15/c1-24-29(59-40(53)34(50)33(27-17-13-11-14-18-27)47-41(54)62-42(4,5)6)22-46(55)38(60-39(52)28-19-15-12-16-20-28)36-44(9,37(51)35(58-25(2)48)32(24)43(46,7)8)30(56-10)21-31-45(36,23-57-31)61-26(3)49/h11-20,29-31,33-36,38,50,55H,21-23H2,1-10H3,(H,47,54)/t29-,30-,31+,33-,34+,35+,36-,38-,44+,45-,46+/m0/s1

Evaluation of Crushed Tablet for Oral Administration and the Effect of Food on Apixaban Pharmacokinetics in Healthy Adults
YanSongPhD1MingChangPhD1AkiyukiSuzukiMS2Robert J.A.FrostMD, PhD3AnneKellyPhD4FrankLaCretaPhD3CharlesFrostPharmD
Clinical Therapeutics Volume 38, Issue 7, July 2016, Pages 1674-1685.e1
 
Development and validation of seven phenyl hydrazine chloro ester isomers (pgis) by rp-hplc-uv method in anticoagulant drug substance; apixaban
Saradhi venkata ramana v.a,b*, durga raja k.a,b, raghu babu k.a, padma m.a, jagadeesh kumar v.b, pavan kumar k. s. r.b, hemant kumar sharma
Int J Curr Pharm Res, Vol 12, Issue 2, 119-123
 
Stability-Indicating High-Perform ance Liquid Chrom atographie Determ ination of Apixaban in the Presence of Degradation Products
Swarup Suresh Prabhune *, Rajendra Shankar Jaguste, Prakash Laxman Kondalkar, Nitin Sharadchandra Pradhan
Sei Pharm. 2014; 82: 777-785
 
Analytical Quality by Design Approach for a Stability‑Indicating Method to Determine Apixaban and Its Related Impurities
Jéssica B. Ellwanger1  · Nathalie Ribeiro Wingert1  · Nadia Maria Volpato1  · Cássia Virginia Garcia1  · Elfrides E. S. Schapoval1  · Martin Steppe
Chromatographia volume 83, pages65–75(2020)