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Apixaban Impurity C

SZ CAT No SZ-A062061
CAS No 1904628-10-9
Mol.F. C27H28N4O6
Mol.Wt. 504.5
Inv. Status In Stock


Chemical Name: 2-Hydroxyethyl 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate

Smiles: O=C1CCCCN1C2=CC=C(N3CCC(C(C(OCCO)=O)=NN4C5=CC=C(OC)C=C5)=C4C3=O)C=C2

Inchi: InChI=1S/C18H18N2O6/c21-14-3-1-2-9-19(14)11-4-6-12(7-5-11)20-10-8-13(15(22)17(20)24)16(23)18(25)26/h4-7,22H,1-3,8-10H2,(H,25,26)

Evaluation of Crushed Tablet for Oral Administration and the Effect of Food on Apixaban Pharmacokinetics in Healthy Adults
YanSongPhD1MingChangPhD1AkiyukiSuzukiMS2Robert J.A.FrostMD, PhD3AnneKellyPhD4FrankLaCretaPhD3CharlesFrostPharmD
Clinical Therapeutics Volume 38, Issue 7, July 2016, Pages 1674-1685.e1
 
Development and validation of seven phenyl hydrazine chloro ester isomers (pgis) by rp-hplc-uv method in anticoagulant drug substance; apixaban
Saradhi venkata ramana v.a,b*, durga raja k.a,b, raghu babu k.a, padma m.a, jagadeesh kumar v.b, pavan kumar k. s. r.b, hemant kumar sharma
Int J Curr Pharm Res, Vol 12, Issue 2, 119-123
 
Stability-Indicating High-Perform ance Liquid Chrom atographie Determ ination of Apixaban in the Presence of Degradation Products
Swarup Suresh Prabhune *, Rajendra Shankar Jaguste, Prakash Laxman Kondalkar, Nitin Sharadchandra Pradhan
Sei Pharm. 2014; 82: 777-785
 
Analytical Quality by Design Approach for a Stability‑Indicating Method to Determine Apixaban and Its Related Impurities
Jéssica B. Ellwanger1  · Nathalie Ribeiro Wingert1  · Nadia Maria Volpato1  · Cássia Virginia Garcia1  · Elfrides E. S. Schapoval1  · Martin Steppe
Chromatographia volume 83, pages65–75(2020)