Apixaban Impurity 75

SZ CAT No:	SZ-A062103
CAS No	5454-83-1
Mol.F.	C6H11BrO2
Mol.Wt.	195.1
Inv. Status	Custom Synthesis

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Chemical Name: Methyl 5-bromopentanoate

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C(OC)CCCCBr

Evaluation of Crushed Tablet for Oral Administration and the Effect of Food on Apixaban Pharmacokinetics in Healthy Adults
YanSongPhD1MingChangPhD1AkiyukiSuzukiMS2Robert J.A.FrostMD, PhD3AnneKellyPhD4FrankLaCretaPhD3CharlesFrostPharmD
Clinical Therapeutics Volume 38, Issue 7, July 2016, Pages 1674-1685.e1

Development and validation of seven phenyl hydrazine chloro ester isomers (pgis) by rp-hplc-uv method in anticoagulant drug substance; apixaban
Saradhi venkata ramana v.a,b*, durga raja k.a,b, raghu babu k.a, padma m.a, jagadeesh kumar v.b, pavan kumar k. s. r.b, hemant kumar sharma
Int J Curr Pharm Res, Vol 12, Issue 2, 119-123

Stability-Indicating High-Perform ance Liquid Chrom atographie Determ ination of Apixaban in the Presence of Degradation Products
Swarup Suresh Prabhune *, Rajendra Shankar Jaguste, Prakash Laxman Kondalkar, Nitin Sharadchandra Pradhan
Sei Pharm. 2014; 82: 777-785

Analytical Quality by Design Approach for a Stability‑Indicating Method to Determine Apixaban and Its Related Impurities
Jéssica B. Ellwanger1 · Nathalie Ribeiro Wingert1 · Nadia Maria Volpato1 · Cássia Virginia Garcia1 · Elfrides E. S. Schapoval1 · Martin Steppe
Chromatographia volume 83, pages65–75(2020)

Apixaban Impurity 75 is chemically Methyl 5-bromopentanoate. Apixaban Impurity 75 is supplied with detailed characterization data compliant with regulatory guideline. Apixaban Impurity 75 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Apixaban.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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SZ CAT No:	: SZ-A062035
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SZ CAT No:	: SZ-A062037
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Apixaban Impurity 31

SZ CAT No:	: SZ-A062042
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SZ CAT No:	: SZ-A062043
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SZ CAT No:	: SZ-A062070
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Mol.Wt.	: 462.5
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Apixaban Impurity 51

SZ CAT No:	: SZ-A062071
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Apixaban Impurity 52

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SZ CAT No:	: SZ-A062073
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Inv. Status	: Custom Synthesis

Apixaban Impurity 54

SZ CAT No:	: SZ-A062074
CAS No	: NA
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Mol.Wt.	: 275.4
Inv. Status	: Custom Synthesis

Apixaban Impurity 55

SZ CAT No:	: SZ-A062075
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Inv. Status	: In Stock

Apixaban Impurity 60

SZ CAT No:	: SZ-A062082
CAS No	: NA
Mol.F.	: C11H9N3O3
Mol.Wt.	: 231.2
Inv. Status	: Custom Synthesis

Apixaban Impurity 61

SZ CAT No:	: SZ-A062083
CAS No	: NA
Mol.F.	: C11H12N2O2
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Apixaban Impurity 63

SZ CAT No:	: SZ-A062085
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Mol.Wt.	: 186.2
Inv. Status	: Custom Synthesis

Apixaban Impurity 64

SZ CAT No:	: SZ-A062086
CAS No	: NA
Mol.F.	: C16H15N3O4
Mol.Wt.	: 313.3
Inv. Status	: Custom Synthesis

Apixaban Impurity 65

SZ CAT No:	: SZ-A062087
CAS No	: NA
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Mol.Wt.	: 268.3
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Apixaban Impurity 66

SZ CAT No:	: SZ-A062088
CAS No	: NA
Mol.F.	: C16H18N2O3
Mol.Wt.	: 286.3
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Mol.Wt.	: 459.5
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