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Empagliflozin Impurity 50

SZ CAT No SZ-E009087
CAS No 1800196-45-5
Mol.F. C18H18BrClO3
Mol.Wt. 397.7
Inv. Status Custom Synthesis


Chemical Name: (3S)-3-(4-((5-bromo-2-chlorophenyl)(methoxy)methyl)phenoxy)tetrahydrofuran

Smiles: COC(C1=CC=C(O[C@H]2CCOC2)C=C1)C(C=C(Br)C=C3)=C3Cl

Stability indicating HPLC-​Fluorescence detection method for the simultaneous determination of linagliptin and empagliflozin in their combined pharmaceutical preparation
By Rizk, Mohamed; Attia, Ali Kamal; Mohamed, Heba Yosry; Elshahed, Mona
From European Journal of Chemistry (2021), 12(2), 168-178
 
Stability indicating hplc method for the quantification of (R)​-​Isomer in empagliflozin drug substance
By Korlakunta, Vijaya Gouri; Sreenivas, N.; Sharma, Hemant Kumar; Nowduri, Annapurna; Bonige, Kishore Babu; Chavakula, Ramadas
From European Journal of Biomedical and Pharmaceutical Sciences (2021), 8(4), 177-184.

Simultaneous determination, validation and forced degradation studies of metformin and empagliflozin using new HPLC analytical method
By Riaz, Muhammad Kashif; Niaz, Sultan; Asghar, Muhammad Arif; Shafiq, Yousra; Zehravi, Mehrukh; Shah, Syed Suffdar Hussain; Abdul Rehman, Ahad; Khan, Kamran
From Latin American Journal of Pharmacy (2020), 39(11), 2257-2265.