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Empagliflozin Impurity 49

SZ CAT No SZ-E009086
CAS No NA
Mol.F. C23H27ClO8
Mol.Wt. 466.9
Inv. Status Custom Synthesis


Chemical Name: (2S,3R,4S,5S,6R)-2-(4-chloro-3-(4-(((R)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetraol

Smiles: O[C@]1(C2=CC=C(Cl)C(CC3=CC=C(O[C@H]4COCC4)C=C3)=C2)[C@@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)O

Inchi: InChI=1S/C30H28N6O3/c1-5-34(20(3)37)26-11-7-9-22(15-26)28(39)14-13-24-18-32-30-25(17-31)19-33-36(30)29(24)23-10-8-12-27(16-23)35(6-2)21(4)38/h7-16,18-19H,5-6H2,1-4H3/b14-13+

Stability indicating HPLC-​Fluorescence detection method for the simultaneous determination of linagliptin and empagliflozin in their combined pharmaceutical preparation
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Stability indicating hplc method for the quantification of (R)​-​Isomer in empagliflozin drug substance
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From European Journal of Biomedical and Pharmaceutical Sciences (2021), 8(4), 177-184.

Simultaneous determination, validation and forced degradation studies of metformin and empagliflozin using new HPLC analytical method
By Riaz, Muhammad Kashif; Niaz, Sultan; Asghar, Muhammad Arif; Shafiq, Yousra; Zehravi, Mehrukh; Shah, Syed Suffdar Hussain; Abdul Rehman, Ahad; Khan, Kamran
From Latin American Journal of Pharmacy (2020), 39(11), 2257-2265.