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Empagliflozin Impurity 36

SZ CAT No SZ-E009070
CAS No NA
Mol.F. C26H44O10
Mol.Wt. 516.6
Inv. Status Custom Synthesis


Chemical Name: (3S,4S,5S)-5-((R)-1,2-dihydroxyethyl)-4-hydroxy-2,3-dipivaloyltetrahydrofuran-2,3-diyl bis(2,2-dimethylpropanoate)

Smiles: O[C@@H]([C@H]([C@@H](CO)O)O1)[C@](OC(C(C)(C)C)=O)(C(C(C)(C)C)=O)C1(C(C(C)(C)C)=O)OC(C(C)(C)C)=O

Inchi: InChI=1S/C21H21ClN2O8/c1-24(2)14-7-5-6-10(16(27)12-9(25)4-3-8(22)11(12)15(6)26)18(29)21(7,32)19(30)13(17(14)28)20(23)31/h3-4,6-7,14-15,25-26,28-29,32H,5H2,1-2H3,(H2,23,31)/t6-,7-,14+,15-,21-/m0/s1

Stability indicating HPLC-​Fluorescence detection method for the simultaneous determination of linagliptin and empagliflozin in their combined pharmaceutical preparation
By Rizk, Mohamed; Attia, Ali Kamal; Mohamed, Heba Yosry; Elshahed, Mona
From European Journal of Chemistry (2021), 12(2), 168-178
 
Stability indicating hplc method for the quantification of (R)​-​Isomer in empagliflozin drug substance
By Korlakunta, Vijaya Gouri; Sreenivas, N.; Sharma, Hemant Kumar; Nowduri, Annapurna; Bonige, Kishore Babu; Chavakula, Ramadas
From European Journal of Biomedical and Pharmaceutical Sciences (2021), 8(4), 177-184.

Simultaneous determination, validation and forced degradation studies of metformin and empagliflozin using new HPLC analytical method
By Riaz, Muhammad Kashif; Niaz, Sultan; Asghar, Muhammad Arif; Shafiq, Yousra; Zehravi, Mehrukh; Shah, Syed Suffdar Hussain; Abdul Rehman, Ahad; Khan, Kamran
From Latin American Journal of Pharmacy (2020), 39(11), 2257-2265.