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Empagliflozin Impurity 45

SZ CAT No SZ-E009082
CAS No NA
Mol.F. C25H29ClO8
Mol.Wt. 492.9
Inv. Status Custom Synthesis


Chemical Name: (2R,3S,4R,5R,6S)-6-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-4,5-dihydroxy-2-(hydroxymethyl)tetrahydro-2H-pyran-3-yl acetate

Smiles: ClC(C=C1)=C(CC2=CC=C(O[C@H]3CCOC3)C=C2)C=C1[C@H]4[C@H](O)[C@@H](O)[C@H](OC(C)=O)[C@@H](CO)O4

Inchi: InChI=1S/C21H28O/c1-4-21-12-13(2)20-17-9-7-16(22)11-15(17)6-8-18(20)19(21)10-5-14(21)3/h11,17-20H,2-10,12H2,1H3/t17-,18-,19-,20+,21+/m0/s1

Stability indicating HPLC-​Fluorescence detection method for the simultaneous determination of linagliptin and empagliflozin in their combined pharmaceutical preparation
By Rizk, Mohamed; Attia, Ali Kamal; Mohamed, Heba Yosry; Elshahed, Mona
From European Journal of Chemistry (2021), 12(2), 168-178
 
Stability indicating hplc method for the quantification of (R)​-​Isomer in empagliflozin drug substance
By Korlakunta, Vijaya Gouri; Sreenivas, N.; Sharma, Hemant Kumar; Nowduri, Annapurna; Bonige, Kishore Babu; Chavakula, Ramadas
From European Journal of Biomedical and Pharmaceutical Sciences (2021), 8(4), 177-184.

Simultaneous determination, validation and forced degradation studies of metformin and empagliflozin using new HPLC analytical method
By Riaz, Muhammad Kashif; Niaz, Sultan; Asghar, Muhammad Arif; Shafiq, Yousra; Zehravi, Mehrukh; Shah, Syed Suffdar Hussain; Abdul Rehman, Ahad; Khan, Kamran
From Latin American Journal of Pharmacy (2020), 39(11), 2257-2265.