Empagliflozin Impurity 28

SZ CAT No:	SZ-E009061
CAS No	32384-65-9
Mol.F.	C18H42O6Si4
Mol.Wt.	466.9
Inv. Status	In Stock

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Chemical Name: (3R,4S,5R,6R)-3,4,5-Tris((trimethylsilyl)oxy)-6-(((trimethylsilyl)oxy)methyl)tetrahydro-2H-pyran-2-one

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C1[C@H](O[Si](C)(C)C)[C@@H](O[Si](C)(C)C)[C@H](O[Si](C)(C)C)[C@@H](CO[Si](C)(C)C)O1

Stability indicating HPLC-Fluorescence detection method for the simultaneous determination of linagliptin and empagliflozin in their combined pharmaceutical preparation
By Rizk, Mohamed; Attia, Ali Kamal; Mohamed, Heba Yosry; Elshahed, Mona
From European Journal of Chemistry (2021), 12(2), 168-178

Stability indicating hplc method for the quantification of (R)-Isomer in empagliflozin drug substance
By Korlakunta, Vijaya Gouri; Sreenivas, N.; Sharma, Hemant Kumar; Nowduri, Annapurna; Bonige, Kishore Babu; Chavakula, Ramadas
From European Journal of Biomedical and Pharmaceutical Sciences (2021), 8(4), 177-184.

Simultaneous determination, validation and forced degradation studies of metformin and empagliflozin using new HPLC analytical method
By Riaz, Muhammad Kashif; Niaz, Sultan; Asghar, Muhammad Arif; Shafiq, Yousra; Zehravi, Mehrukh; Shah, Syed Suffdar Hussain; Abdul Rehman, Ahad; Khan, Kamran
From Latin American Journal of Pharmacy (2020), 39(11), 2257-2265.

Empagliflozin Impurity 28 is chemically (3R,4S,5R,6R)-3,4,5-Tris((trimethylsilyl)oxy)-6-(((trimethylsilyl)oxy)methyl)tetrahydro-2H-pyran-2-one. Empagliflozin Impurity 28 is supplied with detailed characterization data compliant with regulatory guideline. Empagliflozin Impurity 28 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Empagliflozin.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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Empagliflozin

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Empagliflozin Impurity 1

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Empagliflozin Impurity 2

SZ CAT No:	: SZ-E009004
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1-Methoxy Empagliflozin

SZ CAT No:	: SZ-E009005
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Mol.F.	: C24H29ClO8
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Empagliflozin S-Furanose

SZ CAT No:	: SZ-E009006
CAS No	: 1620758-32-8
Mol.F.	: C23H27ClO7
Mol.Wt.	: 450.9
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Empagliflozin α-Anomer

SZ CAT No:	: SZ-E009007
CAS No	: 1620758-33-9
Mol.F.	: C23H27ClO7
Mol.Wt.	: 450.9
Inv. Status	: In Stock

Desglucosylempagliflozin 4,4’-DImer

SZ CAT No:	: SZ-E009008
CAS No	: NA
Mol.F.	: C34H32Cl2O4
Mol.Wt.	: 575.5
Inv. Status	: Custom Synthesis

Empagliflozin Diol impurity (Mixture of Isomer)

SZ CAT No:	: SZ-E009009
CAS No	: NA
Mol.F.	: C23H29ClO8
Mol.Wt.	: 468.9
Inv. Status	: In Stock

Empagliflozin Impurity 5

SZ CAT No:	: SZ-E009010
CAS No	: 1800196-46-6
Mol.F.	: C17H16ClIO3
Mol.Wt.	: 430.7
Inv. Status	: In Stock

Empagliflozin Impurity 6

SZ CAT No:	: SZ-E009011
CAS No	: 1620758-21-5
Mol.F.	: C32H37ClO12
Mol.Wt.	: 649.1
Inv. Status	: In Stock

Empagliflozin MonoAcetyl Impurity

SZ CAT No:	: SZ-E009012
CAS No	: NA
Mol.F.	: C25H29ClO8
Mol.Wt.	: 492.9
Inv. Status	: Limited Stock

Empagliflozin Impurity 7

SZ CAT No:	: SZ-E009013
CAS No	: 333359-90-3
Mol.F.	: C20H23ClO6
Mol.Wt.	: 394.8
Inv. Status	: In Stock

Empagliflozin Keto Impurity

SZ CAT No:	: SZ-E009014
CAS No	: 2125472-55-9
Mol.F.	: C23H25ClO8
Mol.Wt.	: 464.9
Inv. Status	: In Stock

Empagliflozin Impurity 9

SZ CAT No:	: SZ-E009015
CAS No	: 2452301-37-8
Mol.F.	: C18H17ClO4
Mol.Wt.	: 332.8
Inv. Status	: In Stock

Empagliflozin Keto Carboxylic Acid

SZ CAT No:	: SZ-E009016
CAS No	: 2452301-29-8
Mol.F.	: C18H15ClO5
Mol.Wt.	: 346.8
Inv. Status	: In Stock

Tetracetyl Empagliflozin

SZ CAT No:	: SZ-E009017
CAS No	: 915095-99-7
Mol.F.	: C31H35ClO11
Mol.Wt.	: 619.1
Inv. Status	: In Stock

Empagliflozin R-Furanose

SZ CAT No:	: SZ-E009019
CAS No	: 1620758-31-7
Mol.F.	: C23H27ClO7
Mol.Wt.	: 450.9
Inv. Status	: Limited Stock

1-Hydroxy Empagliflozin

SZ CAT No:	: SZ-E009020
CAS No	: 1279691-35-8
Mol.F.	: C23H27ClO8
Mol.Wt.	: 466.9
Inv. Status	: In Stock

Empagliflozin Bromo Impurity

SZ CAT No:	: SZ-E009022
CAS No	: NA
Mol.F.	: C23H27BrO7
Mol.Wt.	: 495.4
Inv. Status	: Out of Stock, Custom Synthesis

Empagliflozin Acetyl impurity

SZ CAT No:	: SZ-E009023
CAS No	: 1079083-63-8
Mol.F.	: C27H29ClO10
Mol.Wt.	: 549.0
Inv. Status	: In Stock

Empagliflozin Methoxy impurity

SZ CAT No:	: SZ-E009024
CAS No	: 872980-38-6
Mol.F.	: C28H31ClO10
Mol.Wt.	: 563.0
Inv. Status	: In Stock

Empagliflozin Keto carboxylic Acid Impurity 2

SZ CAT No:	: SZ-E009025
CAS No	: NA
Mol.F.	: C18H16O5
Mol.Wt.	: 312.3
Inv. Status	: In Stock

Empagliflozin D4

SZ CAT No:	: SZ-E009D01
CAS No	: NA
Mol.F.	: C23H23D4ClO7
Mol.Wt.	: 454.9
Inv. Status	: Custom Synthesis

Empagliflozin D8

SZ CAT No:	: SZ-E009D02
CAS No	: NA
Mol.F.	: C23H19D8ClO7
Mol.Wt.	: 459.0
Inv. Status	: Custom Synthesis

1,4-Anhydro-1,5-Dihydroxy-3-Epi-Empagliflozin D4

SZ CAT No:	: SZ-E009D03
CAS No	: NA
Mol.F.	: C23H23D4ClO7
Mol.Wt.	: 454.9
Inv. Status	: Custom Synthesis

1,4-Anhydro-1,5-Dihydroxy-Empagliflozin D4

SZ CAT No:	: SZ-E009D04
CAS No	: NA
Mol.F.	: C23H23D4ClO7
Mol.Wt.	: 454.9
Inv. Status	: Custom Synthesis

3-Epi Empagliflozin D4

SZ CAT No:	: SZ-E009D05
CAS No	: NA
Mol.F.	: C23H23D4ClO7
Mol.Wt.	: 454.9
Inv. Status	: Custom Synthesis

(1R)-1,5-Dihydroxy Empagliflozin D4

SZ CAT No:	: SZ-E009D06
CAS No	: NA
Mol.F.	: C23H25D4ClO8
Mol.Wt.	: 473.0
Inv. Status	: Custom Synthesis

5-Bromo-2-Chlorobenzoic Acid

SZ CAT No:	: SZ-E009026
CAS No	: 21739-92-4
Mol.F.	: C7H4BrClO2
Mol.Wt.	: 235.5
Inv. Status	: In Stock, 3-4 days for Dispatch
Rel. CAS No	: 1938142-12-1 (Na salt) ; 85793-78-8 (K salt)

Empagliflozin 5-Bromo Hydroxy Analog

SZ CAT No:	: SZ-E009027
CAS No	: 1800196-43-3
Mol.F.	: C17H16BrClO3
Mol.Wt.	: 383.7
Inv. Status	: In Stock

5-Bromo Keto THF Impurity

SZ CAT No:	: SZ-E009028
CAS No	: 915095-84-0
Mol.F.	: C17H14BrClO3
Mol.Wt.	: 381.7
Inv. Status	: In Stock

Empagliflozin Impurity 11

SZ CAT No:	: SZ-E009029
CAS No	: 2452301-27-6
Mol.F.	: C23H28O7
Mol.Wt.	: 416.5
Inv. Status	: In Stock

Empagliflozin Hydroxy Impurity

SZ CAT No:	: SZ-E009030
CAS No	: NA
Mol.F.	: C23H27ClO8
Mol.Wt.	: 466.9
Inv. Status	: In Stock

Empagliflozin R/S Furanose

SZ CAT No:	: SZ-E009031
CAS No	: NA
Mol.F.	: C23H27ClO7
Mol.Wt.	: 450.9
Inv. Status	: Limited Stock

Empagliflozin Desbromo Impurity

SZ CAT No:	: SZ-E009032
CAS No	: 2517968-35-1
Mol.F.	: C17H17ClO2
Mol.Wt.	: 288.8
Inv. Status	: In Stock

5-Bromo Empagliflozin Impurity

SZ CAT No:	: SZ-E009033
CAS No	: 915095-89-5
Mol.F.	: C17H16BrClO2
Mol.Wt.	: 367.7
Inv. Status	: In Stock

Empagliflozin Dimer Impurity

SZ CAT No:	: SZ-E009034
CAS No	: 2864810-38-6
Mol.F.	: C34H32Cl2O4
Mol.Wt.	: 575.5
Inv. Status	: Limited Stock

Empagliflozin Open Ring Impurity

SZ CAT No:	: SZ-E009035
CAS No	: NA
Mol.F.	: C23H29ClO8
Mol.Wt.	: 468.9
Inv. Status	: Custom Synthesis

Empagliflozin Silyll Impurity

SZ CAT No:	: SZ-E009036
CAS No	: 2819995-58-7
Mol.F.	: C20H25ClO2Si
Mol.Wt.	: 361.0
Inv. Status	: Custom Synthesis

Empagliflozin Sulfonate Impurity

SZ CAT No:	: SZ-E009037
CAS No	: 2514922-33-7
Mol.F.	: C10H12O4S
Mol.Wt.	: 228.3
Inv. Status	: In Stock

Empagliflozin Phenolic Acid

SZ CAT No:	: SZ-E009038
CAS No	: NA
Mol.F.	: C21H23ClO7
Mol.Wt.	: 422.9
Inv. Status	: Custom Synthesis

Empagliflozin Impurity 12

SZ CAT No:	: SZ-E009039
CAS No	: NA
Mol.F.	: C19H24ClIOSi
Mol.Wt.	: 458.8
Inv. Status	: Custom Synthesis

Empagliflozin Impurity 13

SZ CAT No:	: SZ-E009040
CAS No	: NA
Mol.F.	: C38H46Cl2I2O2SSi2
Mol.Wt.	: 947.7
Inv. Status	: In Stock

Empagliflozin Impurity 14

SZ CAT No:	: SZ-E009041
CAS No	: 219823-47-9
Mol.F.	: C11H14O4S
Mol.Wt.	: 242.3
Inv. Status	: In Stock

Empagliflozin Impurity 15

SZ CAT No:	: SZ-E009042
CAS No	: NA
Mol.F.	: C27H33ClO8
Mol.Wt.	: 521.0
Inv. Status	: Limited Stock

Empagliflozin Impurity 16

SZ CAT No:	: SZ-E009043
CAS No	: NA
Mol.F.	: C27H33ClO8
Mol.Wt.	: 521.0
Inv. Status	: In Stock

Empagliflozin Hydroxy Impurity

SZ CAT No:	: SZ-E009045
CAS No	: NA
Mol.F.	: C23H28O7
Mol.Wt.	: 416.5
Inv. Status	: Custom Synthesis

Empagliflozin Ortho Isomer

SZ CAT No:	: SZ-E009046
CAS No	: 2452301-30-1
Mol.F.	: C23H27ClO7
Mol.Wt.	: 450.9
Inv. Status	: Custom Synthesis

Empagliflozin Impurity 17

SZ CAT No:	: SZ-E009047
CAS No	: NA
Mol.F.	: C23H27ClO7
Mol.Wt.	: 450.9
Inv. Status	: Under Synthesis

Empagliflozin Impurity 10

SZ CAT No:	: SZ-E009048
CAS No	: NA
Mol.F.	: C23H27ClO8
Mol.Wt.	: 466.9
Inv. Status	: Custom Synthesis

(R)-(-)-3-Hydroxytetrahydrofuran

SZ CAT No:	: SZ-E009049
CAS No	: 86087-24-3
Mol.F.	: C4H8O2
Mol.Wt.	: 88.1
Inv. Status	: In Stock, 3-4 days for Dispatch

(S)-(+)-3-Hydroxytetrahydrofuran

SZ CAT No:	: SZ-E009050
CAS No	: 86087-23-2
Mol.F.	: C4H8O2
Mol.Wt.	: 88.1
Inv. Status	: In Stock, 3-4 days for Dispatch

Empagliflozin Impurity 18

SZ CAT No:	: SZ-E009051
CAS No	: 1806-23-1
Mol.F.	: C13H8ClFO
Mol.Wt.	: 234.7
Inv. Status	: In Stock

Empagliflozin Impurity 19

SZ CAT No:	: SZ-E009052
CAS No	: 46698-24-2
Mol.F.	: C13H8BrFO
Mol.Wt.	: 279.1
Inv. Status	: In Stock
Rel. CAS No	: 16579-67-2 (Sulfate salt)

Empagliflozin Impurity 20

SZ CAT No:	: SZ-E009053
CAS No	: 1360568-68-8
Mol.F.	: C13H8BrClO2
Mol.Wt.	: 311.6
Inv. Status	: In Stock

Empagliflozin Impurity 21

SZ CAT No:	: SZ-E009054
CAS No	: 333361-49-2
Mol.F.	: C14H10BrClO2
Mol.Wt.	: 325.6
Inv. Status	: In Stock

Empagliflozin Impurity 22

SZ CAT No:	: SZ-E009055
CAS No	: 915095-85-1
Mol.F.	: C13H7BrClFO
Mol.Wt.	: 313.6
Inv. Status	: In Stock

Empagliflozin Impurity 23

SZ CAT No:	: SZ-E009056
CAS No	: 915095-90-8
Mol.F.	: C17H16BrClO2
Mol.Wt.	: 367.7
Inv. Status	: In Stock

Empagliflozin Impurity 24

SZ CAT No:	: SZ-E009057
CAS No	: 1280718-70-8
Mol.F.	: C13H9BrClFO
Mol.Wt.	: 315.6
Inv. Status	: In Stock

Empagliflozin Impurity 25

SZ CAT No:	: SZ-E009058
CAS No	: 1628918-33-1
Mol.F.	: C13H9BrClF
Mol.Wt.	: 299.6
Inv. Status	: In Stock

Empagliflozin Impurity 26

SZ CAT No:	: SZ-E009059
CAS No	: 1620758-25-9
Mol.F.	: C24H29ClO8
Mol.Wt.	: 480.9
Inv. Status	: Under Synthesis

Empagliflozin Impurity 27

SZ CAT No:	: SZ-E009060
CAS No	: 1358604-08-6
Mol.F.	: C11H11NO5
Mol.Wt.	: 237.2
Inv. Status	: Custom Synthesis

Empagliflozin Impurity 28

SZ CAT No:	: SZ-E009061
CAS No	: 32384-65-9
Mol.F.	: C18H42O6Si4
Mol.Wt.	: 466.9
Inv. Status	: In Stock

Empagliflozin Impurity 29

SZ CAT No:	: SZ-E009062
CAS No	: 2452301-28-7
Mol.F.	: C23H27ClO7
Mol.Wt.	: 450.9
Inv. Status	: In Stock

Empagliflozin Impurity 30

SZ CAT No:	: SZ-E009063
CAS No	: 2452301-32-3
Mol.F.	: C23H25ClO7
Mol.Wt.	: 448.9
Inv. Status	: Custom Synthesis

Empagliflozin Impurity 31

SZ CAT No:	: SZ-E009064
CAS No	: 96-48-0
Mol.F.	: C4H6O2
Mol.Wt.	: 86.1
Inv. Status	: Custom Synthesis

Empagliflozin Impurity 32

SZ CAT No:	: SZ-E009065
CAS No	: 2137418-13-2
Mol.F.	: C23H27ClO8
Mol.Wt.	: 466.9
Inv. Status	: In Stock

Empagliflozin Diol impurity (S-Isomer)

SZ CAT No:	: SZ-E009066
CAS No	: 2452301-18-5
Mol.F.	: C23H29ClO8
Mol.Wt.	: 468.9
Inv. Status	: Out of Stock, Custom Synthesis

Empagliflozin Impurity 3

SZ CAT No:	: SZ-E009067
CAS No	: 1417573-74-0
Mol.F.	: C23H27ClO7
Mol.Wt.	: 450.9
Inv. Status	: Custom Synthesis

Empagliflozin Impurity 34

SZ CAT No:	: SZ-E009068
CAS No	: NA
Mol.F.	: C23H27ClO7
Mol.Wt.	: 450.9
Inv. Status	: Custom Synthesis

Empagliflozin Impurity 36

SZ CAT No:	: SZ-E009070
CAS No	: NA
Mol.F.	: C26H44O10
Mol.Wt.	: 516.6
Inv. Status	: Custom Synthesis

Empagliflozin Impurity 37

SZ CAT No:	: SZ-E009071
CAS No	: NA
Mol.F.	: C26H45NO10
Mol.Wt.	: 531.6
Inv. Status	: Custom Synthesis

Empagliflozin Impurity 38

SZ CAT No:	: SZ-E009072
CAS No	: 1715629-30-3
Mol.F.	: C13H7BrClFO
Mol.Wt.	: 313.6
Inv. Status	: Custom Synthesis

Empagliflozin Impurity 39

SZ CAT No:	: SZ-E009073
CAS No	: NA
Mol.F.	: C17H16Br2O2
Mol.Wt.	: 412.1
Inv. Status	: In Stock

Empagliflozin Impurity 40

SZ CAT No:	: SZ-E009074
CAS No	: 2744280-76-8
Mol.F.	: C17H16BrClO2
Mol.Wt.	: 367.7
Inv. Status	: In Stock

Empagliflozin Impurity 41

SZ CAT No:	: SZ-E009075
CAS No	: NA
Mol.F.	: C23H27ClO7
Mol.Wt.	: 450.9
Inv. Status	: Custom Synthesis

Empagliflozin Hydroperoxy Impurity

SZ CAT No:	: SZ-E009076
CAS No	: 2452301-14-1
Mol.F.	: C23H27ClO9
Mol.Wt.	: 482.9
Inv. Status	: Custom Synthesis

Empagliflozin Methyl Acetate

SZ CAT No:	: SZ-E009079
CAS No	: 2452301-09-4
Mol.F.	: C25H29ClO8
Mol.Wt.	: 492.9
Inv. Status	: In Stock

Empagliflozin Impurity 43

SZ CAT No:	: SZ-E009080
CAS No	: 2452301-42-5
Mol.F.	: C23H27ClO7
Mol.Wt.	: 450.9
Inv. Status	: In Stock

(1R)-1,5-Dihydroxyempagliflozin

SZ CAT No:	: SZ-E009018
CAS No	: 1620758-34-0
Mol.F.	: C23H29ClO8
Mol.Wt.	: 468.9
Inv. Status	: In Stock

Empagliflozin Impurity 45

SZ CAT No:	: SZ-E009082
CAS No	: NA
Mol.F.	: C25H29ClO8
Mol.Wt.	: 492.9
Inv. Status	: Custom Synthesis

Empagliflozin Impurity 46

SZ CAT No:	: SZ-E009083
CAS No	: NA
Mol.F.	: C25H29ClO8
Mol.Wt.	: 492.9
Inv. Status	: In Stock

Empagliflozin Impurity 47

SZ CAT No:	: SZ-E009084
CAS No	: NA
Mol.F.	: C25H29ClO8
Mol.Wt.	: 492.9
Inv. Status	: Limited Stock

Empagliflozin Impurity 48

SZ CAT No:	: SZ-E009085
CAS No	: NA
Mol.F.	: C23H27ClO7
Mol.Wt.	: 450.9
Inv. Status	: Custom Synthesis

Empagliflozin Impurity 49

SZ CAT No:	: SZ-E009086
CAS No	: NA
Mol.F.	: C23H27ClO8
Mol.Wt.	: 466.9
Inv. Status	: Custom Synthesis

Empagliflozin Impurity 50

SZ CAT No:	: SZ-E009087
CAS No	: 1800196-45-5
Mol.F.	: C18H18BrClO3
Mol.Wt.	: 397.7
Inv. Status	: In Stock

Empagliflozin Dimethoxy Impurity

SZ CAT No:	: SZ-E009088
CAS No	: 1800196-50-2
Mol.F.	: C25H31ClO9
Mol.Wt.	: 511.0
Inv. Status	: In Stock

Empagliflozin Desbromo Methoxy Impurity

SZ CAT No:	: SZ-E009089
CAS No	: NA
Mol.F.	: C18H19ClO3
Mol.Wt.	: 318.8
Inv. Status	: Custom Synthesis

Empagliflozin Dimer Impurity 1

SZ CAT No:	: SZ-E009090
CAS No	: NA
Mol.F.	: C46H52Cl2O14
Mol.Wt.	: 899.8
Inv. Status	: Custom Synthesis

Empagliflozin Impurity 28

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