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Empagliflozin Impurity 48

SZ CAT No SZ-E009085
CAS No NA
Mol.F. C23H27ClO7
Mol.Wt. 450.9
Inv. Status Custom Synthesis


Chemical Name: (2R,3S,4S,5R,6S)-2-(4-chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

Smiles: ClC(C=C1)=C(CC2=CC=C(O[C@@H]3COCC3)C=C2)C=C1[C@@H]4[C@@H](O)[C@H](O)[C@@H](O)[C@H](CO)O4

Inchi: InChI=1S/C25H33N3O10/c29-8-16-18(31)19(32)22(35)25(37-16)38-23-17(9-30)36-24(21(34)20(23)33)28-6-10-3-11(7-28)13-5-15-14(4-12(10)13)26-1-2-27-15/h1-2,4-5,10-11,16-25,29-35H,3,6-9H2/t10?,11?,16-,17-,18-,19+,20-,21-,22-,23-,24-,25?/m1/s1

Stability indicating HPLC-​Fluorescence detection method for the simultaneous determination of linagliptin and empagliflozin in their combined pharmaceutical preparation
By Rizk, Mohamed; Attia, Ali Kamal; Mohamed, Heba Yosry; Elshahed, Mona
From European Journal of Chemistry (2021), 12(2), 168-178
 
Stability indicating hplc method for the quantification of (R)​-​Isomer in empagliflozin drug substance
By Korlakunta, Vijaya Gouri; Sreenivas, N.; Sharma, Hemant Kumar; Nowduri, Annapurna; Bonige, Kishore Babu; Chavakula, Ramadas
From European Journal of Biomedical and Pharmaceutical Sciences (2021), 8(4), 177-184.

Simultaneous determination, validation and forced degradation studies of metformin and empagliflozin using new HPLC analytical method
By Riaz, Muhammad Kashif; Niaz, Sultan; Asghar, Muhammad Arif; Shafiq, Yousra; Zehravi, Mehrukh; Shah, Syed Suffdar Hussain; Abdul Rehman, Ahad; Khan, Kamran
From Latin American Journal of Pharmacy (2020), 39(11), 2257-2265.