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3-Epi Empagliflozin D4

SZ CAT No SZ-E009D05
CAS No NA
Mol.F. C23H23D4ClO7
Mol.Wt. 454.9
Inv. Status Custom Synthesis


Chemical Name: (3R,4R,5S,6R)‐2‐[4̷R)‐Oxolan‐3‐ yloxy](D4)phenyl}methyl)phenyl]‐6‐ (hydroxymethyl)oxane‐3,4,5‐triol.

Smiles: O[C@H]([C@H]1O)[C@@H](O[C@H](CO)[C@H]1O)C2=CC(CC3=C([2H])C([2H])=C(O[C@@H]4CCOC4)C([2H])=C3[2H])=C(Cl)C=C2

Inchi: InChI=1S/C23H27ClO7/c24-18-6-3-14(22-20(27)21(28)23(31-22)19(26)11-25)10-15(18)9-13-1-4-16(5-2-13)30-17-7-8-29-12-17/h1-6,10,17,19-23,25-28H,7-9,11-12H2/t17-,19+,20+,21+,22?,23-/m0/s1/i1D,2D,4D,5D

Stability indicating HPLC-​Fluorescence detection method for the simultaneous determination of linagliptin and empagliflozin in their combined pharmaceutical preparation
By Rizk, Mohamed; Attia, Ali Kamal; Mohamed, Heba Yosry; Elshahed, Mona
From European Journal of Chemistry (2021), 12(2), 168-178
 
Stability indicating hplc method for the quantification of (R)​-​Isomer in empagliflozin drug substance
By Korlakunta, Vijaya Gouri; Sreenivas, N.; Sharma, Hemant Kumar; Nowduri, Annapurna; Bonige, Kishore Babu; Chavakula, Ramadas
From European Journal of Biomedical and Pharmaceutical Sciences (2021), 8(4), 177-184.

Simultaneous determination, validation and forced degradation studies of metformin and empagliflozin using new HPLC analytical method
By Riaz, Muhammad Kashif; Niaz, Sultan; Asghar, Muhammad Arif; Shafiq, Yousra; Zehravi, Mehrukh; Shah, Syed Suffdar Hussain; Abdul Rehman, Ahad; Khan, Kamran
From Latin American Journal of Pharmacy (2020), 39(11), 2257-2265.