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Empagliflozin Impurity 42

SZ CAT No SZ-E009076
CAS No 2452301-14-1
Mol.F. C23H27ClO9
Mol.Wt. 482.9
Inv. Status Custom Synthesis


Chemical Name: (2S,3R,4R,5S,6R)-2-(4-chloro-3-(hydroperoxy(4-(((S)-tetrahydrofuran-3-yl)oxy)phenyl)methyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

Smiles: O[C@H]1[C@H](C2=CC(C(C3=CC=C(O[C@H]4CCOC4)C=C3)OO)=C(Cl)C=C2)O[C@H](CO)[C@@H](O)[C@@H]1O

Inchi: InChI=1S/C37H42F2N8O4/c1-3-35-26(2)50-25-42-47(35)36(48)43-28-5-7-29(8-6-28)44-16-18-45(19-17-44)30-9-11-31(12-10-30)49-21-32-14-15-37(51-32,22-46-24-40-23-41-46)33-13-4-27(38)20-34(33)39/h4-13,20,23-26,32,35H,3,14-19,21-22H2,1-2H3,(H,43,48)/t26?,32-,35-,37+/m1/s1

Stability indicating HPLC-​Fluorescence detection method for the simultaneous determination of linagliptin and empagliflozin in their combined pharmaceutical preparation
By Rizk, Mohamed; Attia, Ali Kamal; Mohamed, Heba Yosry; Elshahed, Mona
From European Journal of Chemistry (2021), 12(2), 168-178
 
Stability indicating hplc method for the quantification of (R)​-​Isomer in empagliflozin drug substance
By Korlakunta, Vijaya Gouri; Sreenivas, N.; Sharma, Hemant Kumar; Nowduri, Annapurna; Bonige, Kishore Babu; Chavakula, Ramadas
From European Journal of Biomedical and Pharmaceutical Sciences (2021), 8(4), 177-184.

Simultaneous determination, validation and forced degradation studies of metformin and empagliflozin using new HPLC analytical method
By Riaz, Muhammad Kashif; Niaz, Sultan; Asghar, Muhammad Arif; Shafiq, Yousra; Zehravi, Mehrukh; Shah, Syed Suffdar Hussain; Abdul Rehman, Ahad; Khan, Kamran
From Latin American Journal of Pharmacy (2020), 39(11), 2257-2265.