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Cabazitaxel Impurity (DiTroc)

SZ CAT No SZ-C056031
CAS No 95603-44-4
Mol.F. C35H38Cl6O14
Mol.Wt. 895.4
Inv. Status In Stock


Chemical Name: (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-9,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4,6-bis(((2,2,2-trichloroethoxy)carbonyl)oxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate

Smiles: CC(O[C@]([C@@]1([H])C[C@@H]2OC(OCC(Cl)(Cl)Cl)=O)(CO1)[C@]([C@@H]([C@]3(C(C)(C)C4=C(C)[C@@H](O)C3)O)OC(C5=CC=CC=C5)=O)([H])[C@@]2(C([C@@H]4OC(OCC(Cl)(Cl)Cl)=O)=O)C)=O

Inchi: InChI=1S/C48H61NO14/c1-26-30(59-41(53)36-34(28-19-15-13-16-20-28)49(45(8,9)62-36)42(54)63-43(3,4)5)24-48(55)39(60-40(52)29-21-17-14-18-22-29)37-46(10,38(51)35(57-12)33(26)44(48,6)7)31(56-11)23-32-47(37,25-58-32)61-27(2)50/h13-22,30-32,34-37,39,55H,23-25H2,1-12H3/t30-,31-,32+,34-,35+,36+,37-,39-,46+,47-,48+/m0/s1

Development and Validation of a Stability-​indicating HPLC Method for the Analysis of Cabazitaxel in Jevtana Concentrate-​solvent Leftover Samples
By Arnamo, Hedvig; Hillebrand, Michel J. X.; Huitema, Alwin D. R.; Nuijen, Bastiaan; Rosing, Hilde; Beijnen, Jos H.
From Current Pharmaceutical Analysis (2021), 17(6), 691-701
 
Development and Validation of a Stability-​Indicating HPLC Method for the Determination of the Impurities in Cabazitaxel
By Li, Chengyan; Lan, Gongjian; Jiang, Jinyuan; Sun, Mingjie; Hang, Taijun
From Chromatographia (2015), 78(11-12), 825-831
 
Development and validation of a stability-​indicating liquid chromatographic method for the assay of cabazitaxel
By Mathrusri Annapurna, M.; Venkatesh, B.; Pramadvara, K.; Hemchand, S.
From Chemical Science Transactions (2014), 3(2), 854-860, 7 pp.