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Cabazitaxel Impurity A

SZ CAT No SZ-C056002
CAS No 183133-94-0
Mol.F. C31H40O10
Mol.Wt. 572.7
Inv. Status In Stock


Chemical Name: [2aR-(2aα,4β,4aβ,6β,9α,11α,12α,12aα,12bα)]-12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-9,11-dihydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-7,11-methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one ; CBT-1A

Synonym: 10-Deacetyl-7,10-dimethoxy-Baccatin III

Smiles: CC(O[C@]([C@@]1([H])C[C@H](OC)[C@]2(C3=O)C)(CO1)[C@@]2([H])[C@@H]([C@@](C4(C)C)(C[C@H](O)C(C)=C4[C@H]3OC)O)OC(C5=CC=CC=C5)=O)=O

Inchi: InChI=1S/C40H57N5O7/c1-6-28(4)35(36(47)40(5)26-52-40)44-39(50)33(24-30-15-11-8-12-16-30)43-38(49)32(23-27(2)3)42-37(48)31(18-17-29-13-9-7-10-14-29)41-34(46)25-45-19-21-51-22-20-45/h7-16,27-28,31-33,35H,6,17-26H2,1-5H3,(H,41,46)(H,42,48)(H,43,49)(H,44,50)/t28-,31-,32-,33-,35-,40-/m0/s1

Development and Validation of a Stability-​indicating HPLC Method for the Analysis of Cabazitaxel in Jevtana Concentrate-​solvent Leftover Samples
By Arnamo, Hedvig; Hillebrand, Michel J. X.; Huitema, Alwin D. R.; Nuijen, Bastiaan; Rosing, Hilde; Beijnen, Jos H.
From Current Pharmaceutical Analysis (2021), 17(6), 691-701
 
Development and Validation of a Stability-​Indicating HPLC Method for the Determination of the Impurities in Cabazitaxel
By Li, Chengyan; Lan, Gongjian; Jiang, Jinyuan; Sun, Mingjie; Hang, Taijun
From Chromatographia (2015), 78(11-12), 825-831
 
Development and validation of a stability-​indicating liquid chromatographic method for the assay of cabazitaxel
By Mathrusri Annapurna, M.; Venkatesh, B.; Pramadvara, K.; Hemchand, S.
From Chemical Science Transactions (2014), 3(2), 854-860, 7 pp.