Cabazitaxel Des-t-BOC Impurity

SZ CAT No:	SZ-C056028
CAS No	1638286-64-2
Mol.F.	C40H49NO12
Mol.Wt.	735.8
Inv. Status	In Stock

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Chemical Name: (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-9-(((2R,3S)-3-amino-2-hydroxy-3-phenylpropanoyl)oxy)-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate;

Synonym: Cabazitaxel Amine

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: CC(O[C@]([C@@]1([H])C[C@H](OC)[C@]2(C3=O)C)(CO1)[C@@]2([H])[C@@H]([C@@](C4(C)C)(C[C@H](OC([C@H](O)[C@H](C5=CC=CC=C5)N)=O)C(C)=C4[C@H]3OC)O)OC(C6=CC=CC=C6)=O)=O

Development and Validation of a Stability-indicating HPLC Method for the Analysis of Cabazitaxel in Jevtana Concentrate-solvent Leftover Samples
By Arnamo, Hedvig; Hillebrand, Michel J. X.; Huitema, Alwin D. R.; Nuijen, Bastiaan; Rosing, Hilde; Beijnen, Jos H.
From Current Pharmaceutical Analysis (2021), 17(6), 691-701

Development and Validation of a Stability-Indicating HPLC Method for the Determination of the Impurities in Cabazitaxel
By Li, Chengyan; Lan, Gongjian; Jiang, Jinyuan; Sun, Mingjie; Hang, Taijun
From Chromatographia (2015), 78(11-12), 825-831

Development and validation of a stability-indicating liquid chromatographic method for the assay of cabazitaxel
By Mathrusri Annapurna, M.; Venkatesh, B.; Pramadvara, K.; Hemchand, S.
From Chemical Science Transactions (2014), 3(2), 854-860, 7 pp.

Cabazitaxel Des-t-BOC Impurity is chemically (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-9-(((2R,3S)-3-amino-2-hydroxy-3-phenylpropanoyl)oxy)-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate; . It is also known as Cabazitaxel Amine. Cabazitaxel Des-t-BOC Impurity is supplied with detailed characterization data compliant with regulatory guideline. Cabazitaxel Des-t-BOC Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cabazitaxel.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Cabazitaxel Des-t-BOC Impurity

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