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Cabazitaxel Impurity 8

SZ CAT No SZ-C056044
CAS No NA
Mol.F. C50H65NO15
Mol.Wt. 920.1
Inv. Status Custom Synthesis


Chemical Name: (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-9-(((2R,3S)-3-(N-(tert-butoxycarbonyl)pivalamido)-2-hydroxy-3-phenylpropanoyl)oxy)-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate

Smiles: O=C([C@H](O)[C@H](C1=CC=CC=C1)N(C(C(C)(C)C)=O)C(OC(C)(C)C)=O)O[C@@H]2C(C)=C([C@@H](OC)C([C@@]3(C)[C@]([C@@]4(OC(C)=O)[C@H](OC4)C[C@@H]3OC)([H])[C@@H]5OC(C6=CC=CC=C6)=O)=O)C(C)(C)[C@@]5(O)C2

Inchi: InChI=1S/C18H35N5O8/c19-4-6-1-2-7(20)17(28-6)30-15-8(21)3-9(22)16(14(15)27)31-18-13(26)11(23)12(25)10(5-24)29-18/h1,7-18,24-27H,2-5,19-23H2/t7-,8+,9-,10+,11-,12+,13+,14+,15-,16+,17-,18+/m1/s1

Development and Validation of a Stability-​indicating HPLC Method for the Analysis of Cabazitaxel in Jevtana Concentrate-​solvent Leftover Samples
By Arnamo, Hedvig; Hillebrand, Michel J. X.; Huitema, Alwin D. R.; Nuijen, Bastiaan; Rosing, Hilde; Beijnen, Jos H.
From Current Pharmaceutical Analysis (2021), 17(6), 691-701
 
Development and Validation of a Stability-​Indicating HPLC Method for the Determination of the Impurities in Cabazitaxel
By Li, Chengyan; Lan, Gongjian; Jiang, Jinyuan; Sun, Mingjie; Hang, Taijun
From Chromatographia (2015), 78(11-12), 825-831
 
Development and validation of a stability-​indicating liquid chromatographic method for the assay of cabazitaxel
By Mathrusri Annapurna, M.; Venkatesh, B.; Pramadvara, K.; Hemchand, S.
From Chemical Science Transactions (2014), 3(2), 854-860, 7 pp.