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Cabazitaxel Impurity 30

SZ CAT No SZ-C056066
CAS No NA
Mol.F. C58H72N2O18
Mol.Wt. 1085.2
Inv. Status Custom Synthesis


Chemical Name: (2aR,4R,4aS,6R,9S,11S,12S,12aR,12bS)-12b-Acetoxy-12-(benzoyloxy)-11-hydroxy-6-methoxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxete-4,9-diyl (2R,2'R,3S,3'S)-bis(3-((tert-butoxycarbonyl)amino)-2-hydroxy-3-phenylpropanoate)

Smiles: CC1=C2C(C)(C)[C@@]([C@@H](OC(C3=CC=CC=C3)=O)[C@@]([C@@]4(OC(C)=O)[C@@](OC4)([H])C[C@H]5OC([C@H](O)[C@@H](NC(OC(C)(C)C)=O)C6=CC=CC=C6)=O)([H])[C@]5(C)C([C@@H]2OC)=O)(O)C[C@@H]1OC([C@H](O)[C@@H](NC(OC(C)(C)C)=O)C7=CC=CC=C7)=O

Inchi: InChI=1S/C30H38O10/c1-15-18(32)13-30(36)25(39-26(35)17-10-8-7-9-11-17)23-28(5,24(34)22(37-6)21(15)27(30,3)4)19(33)12-20-29(23,14-38-20)40-16(2)31/h7-11,18-20,22-23,25,32-33,36H,12-14H2,1-6H3/t18-,19-,20+,22+,23-,25-,28+,29-,30+/m0/s1

Development and Validation of a Stability-​indicating HPLC Method for the Analysis of Cabazitaxel in Jevtana Concentrate-​solvent Leftover Samples
By Arnamo, Hedvig; Hillebrand, Michel J. X.; Huitema, Alwin D. R.; Nuijen, Bastiaan; Rosing, Hilde; Beijnen, Jos H.
From Current Pharmaceutical Analysis (2021), 17(6), 691-701
 
Development and Validation of a Stability-​Indicating HPLC Method for the Determination of the Impurities in Cabazitaxel
By Li, Chengyan; Lan, Gongjian; Jiang, Jinyuan; Sun, Mingjie; Hang, Taijun
From Chromatographia (2015), 78(11-12), 825-831
 
Development and validation of a stability-​indicating liquid chromatographic method for the assay of cabazitaxel
By Mathrusri Annapurna, M.; Venkatesh, B.; Pramadvara, K.; Hemchand, S.
From Chemical Science Transactions (2014), 3(2), 854-860, 7 pp.