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Acemetacin EP Impurity E

SZ CAT No SZ-A089006
CAS No 75302-98-6
Mol.F. C25H26ClNO6
Mol.Wt. 471.9
Inv. Status Custom Synthesis


Chemical Name: 1,1-Dimethylethyl [[[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl]oxy]acetate (as per EP)

Smiles: O=C(OC(C)(C)C)COC(CC1=C(C)N(C(C2=CC=C(Cl)C=C2)=O)C3=C1C=C(OC)C=C3)=O

Inchi: InChI=1S/C25H26ClNO6/c1-14-17(11-23(30)33-13-22(28)29)18-10-21(32-5)19(25(2,3)4)12-20(18)27(14)24(31)15-6-8-16(26)9-7-15/h6-10,12H,11,13H2,1-5H3,(H,28,29)

Stability-​indicating HPLC and PLS chemometric methods for the determination of acemetacin in presence of its degradation products and impurities
By Kessiba, Amira Mohamed; Hegazy, Maha Abdel Monen; Abdelkawy, Mohamed Mohamed; El Gendy, Ahmed Emad
From European Journal of Chemistry (2015), 6(4), 422-429

Development and validation of stability indicating spectrophotometric and HPTLC methods for determination of acemetacin
By Naguib, Ibrahim Ahmed; Abdelhamid Abdelaleem, Eglal; Zaazaa, Hala Elsayed; Abd ElWahab Hussein, Essraa
From European Journal of Chemistry (2014), 5(2), 219-226, 8 pp