Acemetacin EP Impurity B

Stability-​indicating HPLC and PLS chemometric methods for the determination of acemetacin in presence of its degradation products and impurities
By Kessiba, Amira Mohamed; Hegazy, Maha Abdel Monen; Abdelkawy, Mohamed Mohamed; El Gendy, Ahmed Emad
From European Journal of Chemistry (2015), 6(4), 422-429

Development and validation of stability indicating spectrophotometric and HPTLC methods for determination of acemetacin
By Naguib, Ibrahim Ahmed; Abdelhamid Abdelaleem, Eglal; Zaazaa, Hala Elsayed; Abd ElWahab Hussein, Essraa
From European Journal of Chemistry (2014), 5(2), 219-226, 8 pp

Acemetacin EP Impurity B is chemically [1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid (as per EP). It is also known as Indometacin (EP & USP). Acemetacin EP Impurity B is supplied with detailed characterization data compliant with regulatory guideline. Acemetacin EP Impurity B can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Acemetacin.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.