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Acemetacin

SZ CAT No SZ-A089001
CAS No 53164-05-9
Mol.F. C21H18ClNO6
Mol.Wt. 415.8
Inv. Status Custom Synthesis
Rel. CAS No 75511-28-3 (Na salt)


Chemical Name: [[[1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl]oxy]acetic acid (as per EP)

Synonym: Acemet ; Acemethacin ; Acemethazine ; Acemix ; Emflex

Smiles: O=C(C1=CC=C(Cl)C=C1)N2C(C=CC(OC)=C3)=C3C(CC(OCC(O)=O)=O)=C2C

Inchi: InChI=1S/C12H12ClN3O/c1-2-9-10(11(14)16-12(17)15-9)7-3-5-8(13)6-4-7/h3-6H,2H2,1H3,(H3,14,15,16,17)

Stability-​indicating HPLC and PLS chemometric methods for the determination of acemetacin in presence of its degradation products and impurities
By Kessiba, Amira Mohamed; Hegazy, Maha Abdel Monen; Abdelkawy, Mohamed Mohamed; El Gendy, Ahmed Emad
From European Journal of Chemistry (2015), 6(4), 422-429

Development and validation of stability indicating spectrophotometric and HPTLC methods for determination of acemetacin
By Naguib, Ibrahim Ahmed; Abdelhamid Abdelaleem, Eglal; Zaazaa, Hala Elsayed; Abd ElWahab Hussein, Essraa
From European Journal of Chemistry (2014), 5(2), 219-226, 8 pp