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Acemetacin EP Impurity C

SZ CAT No SZ-A089004
Mol.F. C21H17Cl2NO6
Mol.Wt. 450.3
Inv. Status Under Synthesis

Chemical Name: [[[1-(3,4-Dichlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetyl]oxy]acetic acid (as per EP)

Smiles: O=C(O)COC(CC1=C(C)N(C(C2=CC=C(Cl)C(Cl)=C2)=O)C3=C1C=C(OC)C=C3)=O

Inchi: InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)

Stability-​indicating HPLC and PLS chemometric methods for the determination of acemetacin in presence of its degradation products and impurities
By Kessiba, Amira Mohamed; Hegazy, Maha Abdel Monen; Abdelkawy, Mohamed Mohamed; El Gendy, Ahmed Emad
From European Journal of Chemistry (2015), 6(4), 422-429

Development and validation of stability indicating spectrophotometric and HPTLC methods for determination of acemetacin
By Naguib, Ibrahim Ahmed; Abdelhamid Abdelaleem, Eglal; Zaazaa, Hala Elsayed; Abd ElWahab Hussein, Essraa
From European Journal of Chemistry (2014), 5(2), 219-226, 8 pp