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Triamcinolone Impurity 2

SZ CAT No SZ-T028021
CAS No NA
Mol.F. C21H27FO6
Mol.Wt. 394.4
Inv. Status Limited Stock


Chemical Name: (1R,3R,10bR)-10b-fluoro-1,3,11-trihydroxy-1-(hydroxymethyl)-10a,12a-dimethyl-1,3,4,4a,4b,5,6,10a,10b,11,12,12a-dodecahydrochrysene-2,8-dione

Smiles: O=C1C=C2CCC3C(C[C@@H](O)C([C@]4(O)CO)=O)C4(C)CC(O)[C@]3(F)C2(C)C=C1

Inchi: InChI=1S/C24H29FO7/c1-20(2)31-17-10-15-14-6-5-12-9-13(26)7-8-21(12,3)23(14,25)16(27)11-22(15,4)24(17,32-20)18(28)19(29)30/h7-9,14-17,27H,5-6,10-11H2,1-4H3,(H,29,30)/t14-,15-,16-,17+,21-,22-,23-,24-/m0/s1

Δ14-​steroidal impurity: preparation, characterization and evaluation, as well development of new HPLC method in drug substance like Triamcinolone Hexacetonide
By Shah, Tejas J.; Thakore, Anant R.; Chheda, Abhay H.; Desai, Geeta R.; Tandel, Harish S.
From Asian Journal of Pharmaceutical Analysis and Medicinal Chemistry (2020), 8(1), 7-15
 
Resolution and quantitation of triamcinolone acetonide and its coformulated drug in the presence of its impurities and degradation products by HPTLC and HPLC
By Abbas, Samah S.; Hegazy, Maha A.; Hendawy, Hassan A. M.; Weshahy, Soheir A.; Abdelwahab, May H.
From Journal of AOAC International (2018), 101(4), 981-991

Development and validation of a stability-​indicating HPLC-​UV method for the determination of triamcinolone acetonide and its degradation products in an ointment formulation
By van Heugten, A. J. P.; de Boer, W.; de Vries, W. S.; Markesteijn, C. M. A.; Vromans, H.
From Journal of Pharmaceutical and Biomedical Analysis (2018), 149, 265-270