11-Oxo Triamcinolone

SZ CAT No:	SZ-T028023
CAS No	3107-69-5
Mol.F.	C21H25FO6
Mol.Wt.	392.4
Inv. Status	Custom Synthesis

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Chemical Name: (8S,9R,10S,13S,14S,16R,17S)-9-Fluoro-16,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthrene-3,11(6H)-dione

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: F[C@]([C@]1(C=C2)C)(C(C3)=O)[C@](CCC1=CC2=O)([H])[C@@](C[C@H]4O)([H])[C@]3([C@](O)4C(CO)=O)C

Δ14-steroidal impurity: preparation, characterization and evaluation, as well development of new HPLC method in drug substance like Triamcinolone Hexacetonide
By Shah, Tejas J.; Thakore, Anant R.; Chheda, Abhay H.; Desai, Geeta R.; Tandel, Harish S.
From Asian Journal of Pharmaceutical Analysis and Medicinal Chemistry (2020), 8(1), 7-15

Resolution and quantitation of triamcinolone acetonide and its coformulated drug in the presence of its impurities and degradation products by HPTLC and HPLC
By Abbas, Samah S.; Hegazy, Maha A.; Hendawy, Hassan A. M.; Weshahy, Soheir A.; Abdelwahab, May H.
From Journal of AOAC International (2018), 101(4), 981-991

Development and validation of a stability-indicating HPLC-UV method for the determination of triamcinolone acetonide and its degradation products in an ointment formulation
By van Heugten, A. J. P.; de Boer, W.; de Vries, W. S.; Markesteijn, C. M. A.; Vromans, H.
From Journal of Pharmaceutical and Biomedical Analysis (2018), 149, 265-270

11-Oxo Triamcinolone is chemically (8S,9R,10S,13S,14S,16R,17S)-9-Fluoro-16,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthrene-3,11(6H)-dione. 11-Oxo Triamcinolone is supplied with detailed characterization data compliant with regulatory guideline. 11-Oxo Triamcinolone can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Triamcinolone.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

11-Oxo Triamcinolone

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