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Triamcinolone C17 Glyoxilic PG Ester

SZ CAT No SZ-T028018
CAS No 2196227-64-0
Mol.F. C27H35FO8
Mol.Wt. 506.6
Inv. Status In Stock

Chemical Name: 2-Hydroxypropyl 2-((6aS,6bR,7S,8aS,8bS,11aR,12aS,12bS)-6b-fluoro-7-hydroxy-6a,8a,10,10-tetramethyl-4-oxo-1,2,4,6a,6b,7,8,8a,11a,12,12a,12b-dodecahydro-8bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-8b-yl)-2-oxoacetate

Smiles: O=C1C=C2CC[C@@]3([H])[C@]([H])(C[C@@H]4[C@@]5(C(C(OCC(O)C)=O)=O)OC(C)(C)O4)[C@]5(C)C[C@H](O)[C@]3(F)[C@@]2(C)C=C1

Inchi: InChI=1S/C27H37FO8/c1-14(29)13-34-22(33)21(32)27-20(35-23(2,3)36-27)11-18-17-7-6-15-10-16(30)8-9-24(15,4)26(17,28)19(31)12-25(18,27)5/h8-10,14,17-20,22,29,31,33H,6-7,11-13H2,1-5H3/t14?,17-,18-,19-,20+,22?,24-,25-,26-,27-/m0/s1

Δ14-​steroidal impurity: preparation, characterization and evaluation, as well development of new HPLC method in drug substance like Triamcinolone Hexacetonide
By Shah, Tejas J.; Thakore, Anant R.; Chheda, Abhay H.; Desai, Geeta R.; Tandel, Harish S.
From Asian Journal of Pharmaceutical Analysis and Medicinal Chemistry (2020), 8(1), 7-15
Resolution and quantitation of triamcinolone acetonide and its coformulated drug in the presence of its impurities and degradation products by HPTLC and HPLC
By Abbas, Samah S.; Hegazy, Maha A.; Hendawy, Hassan A. M.; Weshahy, Soheir A.; Abdelwahab, May H.
From Journal of AOAC International (2018), 101(4), 981-991

Development and validation of a stability-​indicating HPLC-​UV method for the determination of triamcinolone acetonide and its degradation products in an ointment formulation
By van Heugten, A. J. P.; de Boer, W.; de Vries, W. S.; Markesteijn, C. M. A.; Vromans, H.
From Journal of Pharmaceutical and Biomedical Analysis (2018), 149, 265-270