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Teriflunomide Meta Impurity

SZ CAT No SZ-T015015
CAS No 63927-52-6
Mol.F. C12H9F3N2O2
Mol.Wt. 270.2
Inv. Status Custom Synthesis


Chemical Name: (Z)-2-cyano-3-hydroxy-N-(3-(trifluoromethyl)phenyl)but-2-enamide

Smiles: O=C(/C(C#N)=C(O)/C)NC1=CC(C(F)(F)F)=CC=C1

Inchi: InChI=1S/C13H13N3O/c17-16-2-1-15-12-4-10-8-3-9(7-14-6-8)11(10)5-13(12)16/h1-2,4-5,8-9,14H,3,6-7H2/t8-,9+/m0/s1

Quality-by-design-based development and validation of a stability-indicating UPLC method for quantification of teriflunomide in the presence of degradation products and its application to in-vitro dissolution
Nukendra Prasad Nadella,Venkata Nadh Ratnakaram & N. Srinivasu
Journal of Liquid Chromatography & Related Technologies Volume 40, 2017 - Issue 10 Pages 517-527
 
Development of Validated Stability Indicating HPTLC Method for the Estimation of Teriflunomide in Bulk and Tablet Dosage Form
Karmankar, Snehal; Tajne, M.
Current Pharmaceutical Analysis, Volume 16, Number 7, 2020, pp. 814-822(9)