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Teriflunomide Impurity A

SZ CAT No SZ-T015013
CAS No 202057-74-7
Mol.F. C12H9N3O2
Mol.Wt. 227.2
Inv. Status Custom Synthesis


Chemical Name: (Z)-2-cyano-N-(4-cyanophenyl)-3-hydroxybut-2-enamide

Smiles: N#CC1=CC=C(NC(/C(C#N)=C(C)\O)=O)C=C1

Inchi: InChI=1S/C21H24F2N6O3S/c1-2-5-33-21-25-19(24-13-7-10(13)9-3-4-11(22)12(23)6-9)16-20(26-21)29(28-27-16)14-8-15(30)18(32)17(14)31/h3-4,6,10,13-15,17-18,30-32H,2,5,7-8H2,1H3,(H,24,25,26)/t10-,13-,14+,15-,17-,18+/m0/s1

Quality-by-design-based development and validation of a stability-indicating UPLC method for quantification of teriflunomide in the presence of degradation products and its application to in-vitro dissolution
Nukendra Prasad Nadella,Venkata Nadh Ratnakaram & N. Srinivasu
Journal of Liquid Chromatography & Related Technologies Volume 40, 2017 - Issue 10 Pages 517-527
 
Development of Validated Stability Indicating HPTLC Method for the Estimation of Teriflunomide in Bulk and Tablet Dosage Form
Karmankar, Snehal; Tajne, M.
Current Pharmaceutical Analysis, Volume 16, Number 7, 2020, pp. 814-822(9)