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Teriflunomide

SZ CAT No SZ-T015001
CAS No 163451-81-8
Mol.F. C12H9F3N2O2
Mol.Wt. 270.2
Inv. Status In Stock


Chemical Name: (Z)-2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide

Smiles: O=C(/C(C#N)=C(O)/C)NC1=CC=C(C(F)(F)F)C=C1

Inchi: InChI=1/C20H22N6O3/c1-13(2)18(20(27)29-3)26(25-28)12-14-8-10-15(11-9-14)16-6-4-5-7-17(16)19-21-23-24-22-19/h4-11,13,18H,12H2,1-3H3,(H,21,22,23,24)

Quality-by-design-based development and validation of a stability-indicating UPLC method for quantification of teriflunomide in the presence of degradation products and its application to in-vitro dissolution
Nukendra Prasad Nadella,Venkata Nadh Ratnakaram & N. Srinivasu
Journal of Liquid Chromatography & Related Technologies Volume 40, 2017 - Issue 10 Pages 517-527
 
Development of Validated Stability Indicating HPTLC Method for the Estimation of Teriflunomide in Bulk and Tablet Dosage Form
Karmankar, Snehal; Tajne, M.
Current Pharmaceutical Analysis, Volume 16, Number 7, 2020, pp. 814-822(9)