Montelukast Sodium EP Impurity B

SZ CAT No:	SZ-M031077
CAS No	1146137-52-1
Mol.F.	C35H33ClNO2S : Na
Mol.Wt.	567.2 : 23.0
Inv. Status	Custom Synthesis
Rel. CAS No	918972-54-0 (free base)

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Chemical Name: [1-[[[(1R)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(1-methylethenyl)phenyl]propyl]sulfanyl]methyl]cyclopropyl]acetic acid Sodium salt (as per EP);[1-[[[(1R)-1-[3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(1-methylethenyl)phenyl]propyl]sulfanyl]methyl]cyclopropyl]acetic acid Sodium salt (as per USP)

Synonym: Montelukast Methylstyrene (USP)

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: C=C(C1=CC=CC=C1CC[C@@H](SCC2(CC2)CC([O-])=O)C3=CC=CC(/C=C/C4=NC5=CC(Cl)=CC=C5C=C4)=C3)C.[Na+]

Method development and validation for the simultaneous estimation of montelukast and acebrophylline in bulk and tablet dosage forms by RP-HPLC
By Ankitha, M.; Ashitha, S.; Sri, Ragasudha A.; Latha, Madhavi P. V.; Devi, Uma P.
From Journal of Global Trends in Pharmaceutical Sciences (2021), 12(1), 9173-9179

Montelukast microsuspension with hypromellose for improved stability and oral absorption
By Lee, Ha Ryeong; Park, Hyun Jin; Park, Jun Soo; Park, Dong Woo; Ho, Myoung Jin; Kim, Dong Yoon; Lee, Hyo Chun; Kim, Eun Jeong; Song, Woo Heon; Park, Jun Sang; et al
From International Journal of Biological Macromolecules (2021), 183, 1732-1742

Analytical method development and validation for simultaneous estimation of Bilastine and Montelukast sodium by UV spectrophotometry
By Raj, R. Mohan; Sankar, A. S. K.; Vetrichelvan, T.
From World Journal of Pharmacy and Pharmaceutical Sciences (2021), 10(1), 680-687

Montelukast Sodium EP Impurity B is chemically [1-[[[(1R)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(1-methylethenyl)phenyl]propyl]sulfanyl]methyl]cyclopropyl]acetic acid Sodium salt (as per EP);[1-[[[(1R)-1-[3-[(E)-2-(7-Chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(1-methylethenyl)phenyl]propyl]sulfanyl]methyl]cyclopropyl]acetic acid Sodium salt (as per USP). It is also known as Montelukast Methylstyrene (USP). Montelukast Sodium EP Impurity B is supplied with detailed characterization data compliant with regulatory guideline. Montelukast Sodium EP Impurity B can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Montelukast.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Montelukast Sodium EP Impurity B

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Inv. Status	: Custom Synthesis

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Inv. Status	: Custom Synthesis

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Inv. Status	: In Stock

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