Montelukast Impurity 8

SZ CAT No:	SZ-M031081
CAS No	136476-38-5
Mol.F.	C7H14O6S2
Mol.Wt.	258.3
Inv. Status	Custom Synthesis

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Chemical Name: Cyclopropane-1,1-diylbis(methylene) dimethanesulfonate

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: C[S](OCC1(CC1)CO[S](C)(=O)=O)(=O)=O

Method development and validation for the simultaneous estimation of montelukast and acebrophylline in bulk and tablet dosage forms by RP-HPLC
By Ankitha, M.; Ashitha, S.; Sri, Ragasudha A.; Latha, Madhavi P. V.; Devi, Uma P.
From Journal of Global Trends in Pharmaceutical Sciences (2021), 12(1), 9173-9179

Montelukast microsuspension with hypromellose for improved stability and oral absorption
By Lee, Ha Ryeong; Park, Hyun Jin; Park, Jun Soo; Park, Dong Woo; Ho, Myoung Jin; Kim, Dong Yoon; Lee, Hyo Chun; Kim, Eun Jeong; Song, Woo Heon; Park, Jun Sang; et al
From International Journal of Biological Macromolecules (2021), 183, 1732-1742

Analytical method development and validation for simultaneous estimation of Bilastine and Montelukast sodium by UV spectrophotometry
By Raj, R. Mohan; Sankar, A. S. K.; Vetrichelvan, T.
From World Journal of Pharmacy and Pharmaceutical Sciences (2021), 10(1), 680-687

Montelukast Impurity 8 is chemically Cyclopropane-1,1-diylbis(methylene) dimethanesulfonate. Montelukast Impurity 8 is supplied with detailed characterization data compliant with regulatory guideline. Montelukast Impurity 8 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Montelukast.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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Montelukast (3R)-Hydroxy Benzoate

SZ CAT No:	: SZ-M031043
CAS No	: 150026-72-5
Mol.F.	: C28H24ClNO3
Mol.Wt.	: 458.0
Inv. Status	: Custom Synthesis

Montelukast (3R)-Hydroxy Propanol

SZ CAT No:	: SZ-M031044
CAS No	: 150026-75-8
Mol.F.	: C29H28ClNO2
Mol.Wt.	: 458.0
Inv. Status	: In Stock

Montelukast (3RS)-Hydroxy Propanol

SZ CAT No:	: SZ-M031045
CAS No	: 959235-68-8
Mol.F.	: C29H28ClNO2
Mol.Wt.	: 458.0
Inv. Status	: In Stock

Montelukast (3S)-Hydroxy Benzoate

SZ CAT No:	: SZ-M031046
CAS No	: 142569-69-5
Mol.F.	: C28H24ClNO3
Mol.Wt.	: 458.0
Inv. Status	: In Stock

Montelukast (3S)-Hydroxy Methoxymethoxy Impurity

SZ CAT No:	: SZ-M031047
CAS No	: 184764-20-3
Mol.F.	: C31H32ClNO4
Mol.Wt.	: 518.0
Inv. Status	: Custom Synthesis

Montelukast (3S)-Hydroxy Methylketone

SZ CAT No:	: SZ-M031048
CAS No	: 184764-13-4
Mol.F.	: C28H24ClNO2
Mol.Wt.	: 442.0
Inv. Status	: In Stock

Montelukast (3S)-Hydroxy Propanol

SZ CAT No:	: SZ-M031049
CAS No	: 142569-70-8
Mol.F.	: C29H28ClNO2
Mol.Wt.	: 458.0
Inv. Status	: In Stock

Montelukast (R)-Hydroxy Metabolite

SZ CAT No:	: SZ-M031050
CAS No	: 184763-26-6
Mol.F.	: C35H36ClNO4S
Mol.Wt.	: 602.2
Inv. Status	: Custom Synthesis

Montelukast (S)-Hydroxy Metabolite

SZ CAT No:	: SZ-M031051
CAS No	: 184763-29-9
Mol.F.	: C35H36ClNO4S
Mol.Wt.	: 602.2
Inv. Status	: Custom Synthesis

Montelukast 1,2-Diol

SZ CAT No:	: SZ-M031052
CAS No	: 186352-97-6
Mol.F.	: C35H36ClNO4S
Mol.Wt.	: 602.2
Inv. Status	: Custom Synthesis

Montelukast 3-Oxo Benzoate

SZ CAT No:	: SZ-M031053
CAS No	: 149968-11-6
Mol.F.	: C28H22ClNO3
Mol.Wt.	: 455.9
Inv. Status	: In Stock

Montelukast

SZ CAT No:	: SZ-M031000
CAS No	: 158966-92-8
Mol.F.	: C35H36ClNO3S
Mol.Wt.	: 586.2
Inv. Status	: In Stock
Rel. CAS No	: 151767-02-1 (Na salt) ; 577953-87-8 (K salt) ; 577953-88-9 (Dicyclohexylamine salt)

Montelukast Acid Methyl Ester

SZ CAT No:	: SZ-M031054
CAS No	: 855473-51-7
Mol.F.	: C36H38ClNO3S
Mol.Wt.	: 600.2
Inv. Status	: In Stock

Montelukast Acyl-β-D-Glucuronide Acetate

SZ CAT No:	: SZ-M031055
CAS No	: 188717-17-1
Mol.F.	: C43H48ClNO11S
Mol.Wt.	: 822.4
Inv. Status	: Custom Synthesis

Montelukast Amide

SZ CAT No:	: SZ-M031056
CAS No	: 866923-63-9
Mol.F.	: C35H37ClN2O2S
Mol.Wt.	: 585.2
Inv. Status	: In Stock

Montelukast Dicarboxylic Acid

SZ CAT No:	: SZ-M031057
CAS No	: 213380-27-9
Mol.F.	: C35H34ClNO5S
Mol.Wt.	: 616.2
Inv. Status	: Custom Synthesis

Montelukast Dicyclohexylamine

SZ CAT No:	: SZ-M031058
CAS No	: 577953-88-9
Mol.F.	: C35H36ClNO3S : C12H23N
Mol.Wt.	: 586.2 : 181.3
Inv. Status	: In Stock
Rel. CAS No	: 151767-02-1 (Na salt) ; 577953-87-8 (K salt) ; 158966-92-8 (free base)

Montelukast Dihydro Impurity

SZ CAT No:	: SZ-M031059
CAS No	: 142147-98-6
Mol.F.	: C35H38ClNO3S : Na
Mol.Wt.	: 588.2 : 23.0
Inv. Status	: Out of Stock
Rel. CAS No	: 142147-67-9 (Free base)

Montelukast Disulfide Diacid Impurity

SZ CAT No:	: SZ-M031060
CAS No	: 162515-67-5
Mol.F.	: C12H18O4S2
Mol.Wt.	: 290.4
Inv. Status	: In Stock

Montelukast Disulfide Dimethyl Ester

SZ CAT No:	: SZ-M031061
CAS No	: 1446481-28-2
Mol.F.	: C14H22O4S2
Mol.Wt.	: 318.5
Inv. Status	: In Stock

Montelukast Sodium EP Impurity A

SZ CAT No:	: SZ-M031021
CAS No	: 190078-45-6
Mol.F.	: C35H35ClNNaO3S
Mol.Wt.	: 608.2
Inv. Status	: In Stock
Rel. CAS No	: 220927-27-5 (free base)

Montelukast EP Impurity B

SZ CAT No:	: SZ-M031022
CAS No	: 918972-54-0
Mol.F.	: C35H34ClNO2S
Mol.Wt.	: 568.2
Inv. Status	: In Stock
Rel. CAS No	: 1146137-52-1 (Na salt)

Montelukast EP Impurity D

SZ CAT No:	: SZ-M031024
CAS No	: 1187586-61-3
Mol.F.	: C41H46ClNO5S2
Mol.Wt.	: 732.4
Inv. Status	: In Stock

Montelukast EP Impurity E

SZ CAT No:	: SZ-M031025
CAS No	: 1187586-58-8
Mol.F.	: C41H46ClNO5S2
Mol.Wt.	: 732.4
Inv. Status	: In Stock

Montelukast EP Impurity F

SZ CAT No:	: SZ-M031026
CAS No	: 937275-23-5
Mol.F.	: C34H32ClNO3S
Mol.Wt.	: 570.1
Inv. Status	: In Stock

Montelukast EP Impurity G

SZ CAT No:	: SZ-M031027
CAS No	: 774538-96-4
Mol.F.	: C35H36ClNO3S
Mol.Wt.	: 586.2
Inv. Status	: In Stock
Rel. CAS No	: 1428448-96-7 (Na salt)

Montelukast EP Impurity H

SZ CAT No:	: SZ-M031028
CAS No	: 851755-56-1
Mol.F.	: C34H32ClNO4S
Mol.Wt.	: 586.1
Inv. Status	: In Stock
Rel. CAS No	: 2244776-97-2 (Na salt) ; 906107-37-7 (HCl salt)

Montelukast EP Impurity I

SZ CAT No:	: SZ-M031029
CAS No	: 2045402-27-3
Mol.F.	: C35H36ClNO4S
Mol.Wt.	: 602.2
Inv. Status	: Out of Stock

Montelukast Ether Impurity

SZ CAT No:	: SZ-M031030
CAS No	: 168214-67-3
Mol.F.	: C29H26ClNO
Mol.Wt.	: 440.0
Inv. Status	: In Stock

Montelukast Ketocarbinol Impurity

SZ CAT No:	: SZ-M031031
CAS No	: 2682015-83-2
Mol.F.	: C34H32ClNO4S
Mol.Wt.	: 586.1
Inv. Status	: Custom Synthesis

Montelukast Ketone Impurity

SZ CAT No:	: SZ-M031032
CAS No	: 1258428-71-5
Mol.F.	: C29H26ClNO2
Mol.Wt.	: 456.0
Inv. Status	: Limited Stock

Montelukast Lactone

SZ CAT No:	: SZ-M031033
CAS No	: 1100617-38-6
Mol.F.	: C27H20ClNO2
Mol.Wt.	: 425.9
Inv. Status	: Custom Synthesis

Montelukast Mercapto Acid Impurity

SZ CAT No:	: SZ-M031034
CAS No	: 162515-68-6
Mol.F.	: C6H10O2S
Mol.Wt.	: 146.2
Inv. Status	: In Stock
Rel. CAS No	: 952585-15-8 (Na salt) ; 952585-16-9 (K salt)

Montelukast Methoxymethoxy Impurity

SZ CAT No:	: SZ-M031035
CAS No	: 184764-27-0
Mol.F.	: C37H40ClNO5S
Mol.Wt.	: 646.2
Inv. Status	: Custom Synthesis

Montelukast Methyl Ether

SZ CAT No:	: SZ-M031036
CAS No	: 1351973-25-5
Mol.F.	: C36H38ClNO3S
Mol.Wt.	: 600.2
Inv. Status	: In Stock

Montelukast Nitrile Impurity

SZ CAT No:	: SZ-M031037
CAS No	: 866923-62-8
Mol.F.	: C35H35ClN2OS
Mol.Wt.	: 567.2
Inv. Status	: Out of Stock

Montelukast Racemate

SZ CAT No:	: SZ-M031038
CAS No	: 220927-26-4
Mol.F.	: C35H36ClNO3S
Mol.Wt.	: 586.2
Inv. Status	: In Stock

Montelukast Sodium

SZ CAT No:	: SZ-M031039
CAS No	: 151767-02-1
Mol.F.	: C35H35ClNNaO3S
Mol.Wt.	: 608.2
Inv. Status	: In Stock
Rel. CAS No	: 158966-92-8 (free base) ; 577953-87-8 (K salt); 577953-88-9 (Dicyclohexylamine salt)

Montelukast Sulfone

SZ CAT No:	: SZ-M031040
CAS No	: 1266620-74-9
Mol.F.	: C35H36ClNO5S
Mol.Wt.	: 618.2
Inv. Status	: Custom Synthesis

Montelukast Impurity

SZ CAT No:	: SZ-M031041
CAS No	: 152922-86-6
Mol.F.	: C7H11NO3S
Mol.Wt.	: 189.2
Inv. Status	: In Stock

Montelukast EP Impurity D / E

SZ CAT No:	: SZ-M031042
CAS No	: 1242260-05-4
Mol.F.	: C41H46ClNO5S2
Mol.Wt.	: 732.4
Inv. Status	: In Stock

Montelukast Chloroalcohol impurity

SZ CAT No:	: SZ-M031062
CAS No	: 880769-28-8
Mol.F.	: C29H27CI2NO
Mol.Wt.	: 476.4
Inv. Status	: Limited Stock

Montelukast-D6 Sodium Salt

SZ CAT No:	: SZ-M031D01
CAS No	: 2673270-26-1
Mol.F.	: C35H29D6ClNO3S : Na
Mol.Wt.	: 591.2 : 23.0
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1093746-29-2 (free base)

Montelukast Dehydro Impurity

SZ CAT No:	: SZ-M031063
CAS No	: 168214-68-4
Mol.F.	: C29H26ClNO
Mol.Wt.	: 440.0
Inv. Status	: Custom Synthesis

Montelukast Impurity 1

SZ CAT No:	: SZ-M031064
CAS No	: 866923-64-0
Mol.F.	: C6H9NS
Mol.Wt.	: 127.2
Inv. Status	: Custom Synthesis
Rel. CAS No	: 1003002-67-2 (Na salt)

Montelukast KSM-II Lactone Impurity

SZ CAT No:	: SZ-M031066
CAS No	: 162515-66-4
Mol.F.	: C6H8OS
Mol.Wt.	: 128.2
Inv. Status	: Custom Synthesis

Montelukast Impurity 3

SZ CAT No:	: SZ-M031067
CAS No	: 152922-71-9
Mol.F.	: C6H9NO
Mol.Wt.	: 111.1
Inv. Status	: In Stock

Montelukast Impurity 4

SZ CAT No:	: SZ-M031068
CAS No	: NA
Mol.F.	: C45H56ClNO5S2
Mol.Wt.	: 790.5
Inv. Status	: In Stock

Montelukast EP Impurity C

SZ CAT No:	: SZ-M031070
CAS No	: 909849-96-3
Mol.F.	: C35H36ClNO4S
Mol.Wt.	: 602.2
Inv. Status	: In Stock
Rel. CAS No	: 909796-71-0 (Na salt)

Montelukast Thioglucolate Analog

SZ CAT No:	: SZ-M031071
CAS No	: NA
Mol.F.	: C45H56ClNO5S2
Mol.Wt.	: 790.5
Inv. Status	: Out of Stock

Montelukast R-Sulfoxide

SZ CAT No:	: SZ-M031072
CAS No	: 184763-47-1
Mol.F.	: C35H36ClNO4S
Mol.Wt.	: 602.2
Inv. Status	: In Stock

cis-Montelukast Sulfoxide

SZ CAT No:	: SZ-M031075
CAS No	: 1428448-97-8
Mol.F.	: C35H35ClNO4S : Na
Mol.Wt.	: 601.2 : 23.0
Inv. Status	: In Stock
Rel. CAS No	: 1428511-42-5 (free base)

Montelukast Potassium

SZ CAT No:	: SZ-M031076
CAS No	: 577953-87-8
Mol.F.	: C35H35ClNO3S : K
Mol.Wt.	: 585.2 : 39.1
Inv. Status	: Custom Synthesis
Rel. CAS No	: 158966-92-8 (free base) ; 151767-02-1 (Na salt) ; 577953-88-9 (Dicyclohexylamine salt)

Montelukast Sodium EP Impurity B

SZ CAT No:	: SZ-M031077
CAS No	: 1146137-52-1
Mol.F.	: C35H33ClNO2S : Na
Mol.Wt.	: 567.2 : 23.0
Inv. Status	: Custom Synthesis
Rel. CAS No	: 918972-54-0 (free base)

Montelukast Sodium EP Impurity G

SZ CAT No:	: SZ-M031078
CAS No	: 1428448-96-7
Mol.F.	: C35H35ClNO3S : Na
Mol.Wt.	: 585.2 : 23.0
Inv. Status	: Custom Synthesis
Rel. CAS No	: 774538-96-4 (free base)

Montelukast Impurity 8

SZ CAT No:	: SZ-M031081
CAS No	: 136476-38-5
Mol.F.	: C7H14O6S2
Mol.Wt.	: 258.3
Inv. Status	: Custom Synthesis

Montelukast Impurity 9

SZ CAT No:	: SZ-M031082
CAS No	: 807638-71-7
Mol.F.	: C30H30ClNO4S
Mol.Wt.	: 536.1
Inv. Status	: Custom Synthesis

Montelukast Impurity 10

SZ CAT No:	: SZ-M031083
CAS No	: NA
Mol.F.	: C45H56ClNO5S2
Mol.Wt.	: 790.5
Inv. Status	: In Stock

Montelukast Impurity 11

SZ CAT No:	: SZ-M031084
CAS No	: 855473-50-6
Mol.F.	: C7H11BrO2
Mol.Wt.	: 207.1
Inv. Status	: Custom Synthesis

Montelukast Impurity 12

SZ CAT No:	: SZ-M031085
CAS No	: 3580-97-0
Mol.F.	: C7H11Br3O2
Mol.Wt.	: 366.9
Inv. Status	: Custom Synthesis

Montelukast S-Sulfoxide

SZ CAT No:	: SZ-M031086
CAS No	: 184763-44-8
Mol.F.	: C35H36ClNO4S
Mol.Wt.	: 602.2
Inv. Status	: In Stock

Montelukast Impurity 8

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