Donepezil Open Ring Impurity (sodium salt) (USP)

SZ CAT No:	SZ-D003026
CAS No	NA
Mol.F.	C24H28NO5 : Na
Mol.Wt.	410.5 : 23.0
Inv. Status	In Stock
Rel. CAS No	197010-25-6 (free base) ; 2217617-87-1 (HCl salt)

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Chemical Name: Sodium 2-(3-(1-benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoate (as per USP)

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: COC1=C(OC)C=C(C([O-])=O)C(CC(CC2CCN(CC3=CC=CC=C3)CC2)=O)=C1.[Na+]

New gradient high-performance liquid chromatography method for determination of donepezil hydrochloride assay and impurities content in oral pharmaceutical formulation
Stella Kafkala ∗, Stella Matthaiou, Pandora Alexaki, Morfis Abatzis, Antonios Bartzeliotis, Maria Katsiabani
Journal of Chromatography A, 1189 (2008) 392–397

Identification and characterization of potential impurities of donepezil
K.V.S.R. Krishna Reddy a, J. Moses Babu a, P. Anil Kumar b, E.R.R. Chandrashekar b, Vijayavitthal T. Mathad b, S. Eswaraiah b, M. Satyanarayana Reddy b, K. Vyas
Journal of Pharmaceutical and Biomedical Analysis 35 (2004) 1047–1058

An Improved and Efficient Process for the Production of Donepezil Hydrochloride: Substitution of Sodium Hydroxide for n-Butyl Lithium via Phase Transfer Catalysis
Navanath Niphade, Anil Mali, Kunal Jagtap, Ramesh Chandra Ojha, Pravinchandra J. Vankawala, and Vijayavitthal T. Mathad
Organic Process Research & Development 2008, 12, 731–735

Analytical Method Development and Validation for the Analysis of Donepezil Hydrochloride and Its Related Substances Using Ultra Perfomance Liquid Chromatography
Mahalingam V* , Kalaivani R A, Somanathan T, Vijayabaskar S
International Journal of Pharmaceutical and Clinical Research 2017; 9(5): 417-424

Donepezil Open Ring Impurity (sodium salt) (USP) is chemically Sodium 2-(3-(1-benzylpiperidin-4-yl)-2-oxopropyl)-4,5-dimethoxybenzoate (as per USP). Donepezil Open Ring Impurity (sodium salt) (USP) is supplied with detailed characterization data compliant with regulatory guideline. Donepezil Open Ring Impurity (sodium salt) (USP) can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Donepezil.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Donepezil Open Ring Impurity (sodium salt) (USP)

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SZ CAT No:	: SZ-D003D06
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Mol.F.	: C23H22D5NO3
Mol.Wt.	: 370.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-D003054
CAS No	: 220170-73-0
Mol.F.	: C29H35NO9
Mol.Wt.	: 541.6
Inv. Status	: Custom Synthesis

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Mol.F.	: C24H29NO2
Mol.Wt.	: 363.5
Inv. Status	: In Stock

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Mol.F.	: C24H31NO2 : HCl
Mol.Wt.	: 365.5 : 36.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-D003040
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Mol.F.	: C24H29NO3
Mol.Wt.	: 379.5
Inv. Status	: In Stock

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Mol.F.	: C13H17NO
Mol.Wt.	: 203.3
Inv. Status	: In Stock

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Mol.F.	: C17H15NO4
Mol.Wt.	: 297.3
Inv. Status	: In Stock

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Mol.F.	: C17H151NO4
Mol.Wt.	: 297.3
Inv. Status	: Custom Synthesis

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Mol.F.	: C31H36NO3 : Br
Mol.Wt.	: 470.6 : 79.9
Inv. Status	: In Stock

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CAS No	: 1207959-41-8
Mol.F.	: C24H23D6NO3
Mol.Wt.	: 385.5
Inv. Status	: Custom Synthesis

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Mol.F.	: C24H22D7NO3
Mol.Wt.	: 386.5
Inv. Status	: In Stock

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CAS No	: 220170-71-8
Mol.F.	: C22H25NO3
Mol.Wt.	: 351.4
Inv. Status	: Custom Synthesis

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Mol.F.	: C24H31NO3
Mol.Wt.	: 381.5
Inv. Status	: In Stock

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Mol.F.	: C17H23NO3
Mol.Wt.	: 289.4
Inv. Status	: In Stock

SZ CAT No:	: SZ-D003045
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Mol.F.	: C17H23NO3 : HCl
Mol.Wt.	: 289.4 : 36.5
Inv. Status	: In Stock

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Mol.F.	: C11H12O3
Mol.Wt.	: 192.2
Inv. Status	: In Stock

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CAS No	: NA
Mol.F.	: C24H29NO4
Mol.Wt.	: 395.5
Inv. Status	: Custom Synthesis

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CAS No	: 4803-57-0
Mol.F.	: C17H17NO3
Mol.Wt.	: 283.3
Inv. Status	: In Stock

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Mol.F.	: C24H24NO3 : Br
Mol.Wt.	: 374.5 : 79.9
Inv. Status	: In Stock

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CAS No	: 145546-80-1
Mol.F.	: C24H27NO3
Mol.Wt.	: 377.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-D003039
CAS No	: 2452407-72-4
Mol.F.	: C24H27NO3
Mol.Wt.	: 377.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-D003001
CAS No	: 120011-70-3
Mol.F.	: C24H29NO3 : HCl
Mol.Wt.	: 379.5 : 36.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-D003052
CAS No	: 884740-09-4
Mol.F.	: C24H29NO3 : HCl : H2O
Mol.Wt.	: 379.5 : 36.5 : 18.0
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-D003015
CAS No	: NA
Mol.F.	: C24H31NO5
Mol.Wt.	: 413.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-D003036
CAS No	: 2230493-73-7
Mol.F.	: C24H27NO3
Mol.Wt.	: 377.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-D003037
CAS No	: NA
Mol.F.	: C24H25NO4
Mol.Wt.	: 391.5
Inv. Status	: Out of Stock

SZ CAT No:	: SZ-D003041
CAS No	: 608511-44-0
Mol.F.	: C24H27NO3
Mol.Wt.	: 377.5
Inv. Status	: In Stock

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Mol.F.	: C24H29NO4
Mol.Wt.	: 395.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-D003043
CAS No	: NA
Mol.F.	: C17H23NO3
Mol.Wt.	: 289.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-D003044
CAS No	: 1034439-43-4
Mol.F.	: C17H25NO2 : HCl
Mol.Wt.	: 275.4 : 36.5
Inv. Status	: Custom Synthesis