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Donepezil Related Products


SynZeal is a leading innovator in pharmaceutical reference standards. We supply high-quality Reference Standards of Donepezil, pharmacopeial and non-pharmacopeial Donepezil impurities, metabolites, stable isotope products, and nitrosamines (N-NO products). Donepezil impurities reference standards are useful in pharmaceutical research. They are useful in product development, ANDA and DMF filing, quality control (QC), method validation, and stability studies. It is also useful in the identification of unknown impurities and the assessment of genotoxic potential.

Donepezil-related products are thoroughly characterized. Donepezil products are supplied with detailed COA & analytical data meeting regulatory compliance. We can also provide EP/USP traceable standards based on your requirements. The supplied products are re-tested at regular intervals.

Pharmaceutical Reference Standards

3-Keto Donepezil

Picture of 3-Keto Donepezil
SZ CAT No:: SZ-D003029
CAS No: 1023500-88-0
Mol.F.: C24H27NO4 
Mol.Wt.: 393.5
Inv. Status: In Stock

Dehydrodeoxy Donepezil

Picture of Dehydrodeoxy Donepezil
SZ CAT No:: SZ-D003007
CAS No: 120013-45-8
Mol.F.: C24H29NO2
Mol.Wt.: 363.5
Inv. Status: In Stock

Deoxy Donepezil

Picture of Deoxy Donepezil
SZ CAT No:: SZ-D003008
CAS No: 1034439-57-0
Mol.F.: C24H31NO2 : HCl
Mol.Wt.: 365.5 : 36.5
Inv. Status: In Stock
Rel. CAS No: 844694-84-4 (free base)

Donepezil

Picture of Donepezil
SZ CAT No:: SZ-D003040
CAS No: 120014-06-4
Mol.F.: C24H29NO3
Mol.Wt.: 379.5
Inv. Status: In Stock

Donepezil Aldehyde Impurity

Picture of Donepezil Aldehyde Impurity
SZ CAT No:: SZ-D003014
CAS No: 22065-85-6
Mol.F.: C13H17NO
Mol.Wt.: 203.3
Inv. Status: In Stock

Donepezil Benzyl Bromide

Picture of Donepezil Benzyl Bromide
SZ CAT No:: SZ-D003006
CAS No: 844694-85-5
Mol.F.: C31H36NO3 : Br
Mol.Wt.: 470.6 : 79.9
Inv. Status: In Stock
Rel. CAS No: 845252-34-8 (free base)

Donepezil Dihydro Impurity

Picture of Donepezil Dihydro Impurity
SZ CAT No:: SZ-D003016
CAS No: 120012-04-6
Mol.F.: C24H31NO3
Mol.Wt.: 381.5
Inv. Status: In Stock

Donepezil EP Impurity A

Picture of Donepezil EP Impurity A
SZ CAT No:: SZ-D003009
CAS No: 120014-30-4
Mol.F.: C17H23NO3
Mol.Wt.: 289.4
Inv. Status: In Stock

Donepezil EP Impurity A (HCl)

Picture of Donepezil EP Impurity A (HCl)
SZ CAT No:: SZ-D003045
CAS No: 120013-39-0
Mol.F.: C17H23NO3 : HCl
Mol.Wt.: 289.4 : 36.5
Inv. Status: In Stock
Rel. CAS No: 120014-30-4 (free base)

Donepezil EP Impurity B

Picture of Donepezil EP Impurity B
SZ CAT No:: SZ-D003024
CAS No: 2107-69-9
Mol.F.: C11H12O3
Mol.Wt.: 192.2
Inv. Status: In Stock

Donepezil EP Impurity D

Picture of Donepezil EP Impurity D
SZ CAT No:: SZ-D003013
CAS No: 4803-57-0
Mol.F.: C17H17NO3
Mol.Wt.: 283.3
Inv. Status: In Stock

Donepezil EP Impurity E

Picture of Donepezil EP Impurity E
SZ CAT No:: SZ-D003031
CAS No: 231283-82-2
Mol.F.: C24H24NO3 : Br
Mol.Wt.: 374.5 : 79.9
Inv. Status: In Stock
Rel. CAS No: 757173-38-9 (free base)

Donepezil EP Impurity F

Picture of Donepezil EP Impurity F
SZ CAT No:: SZ-D003002
CAS No: 145546-80-1
Mol.F.: C24H27NO3
Mol.Wt.: 377.5
Inv. Status: In Stock

Donepezil EP Impurity H

Picture of Donepezil EP Impurity H
SZ CAT No:: SZ-D003041
CAS No: 608511-44-0
Mol.F.: C24H27NO3
Mol.Wt.: 377.5
Inv. Status: In Stock

Donepezil Hydrochloride

Picture of Donepezil Hydrochloride
SZ CAT No:: SZ-D003001
CAS No: 120011-70-3
Mol.F.: C24H29NO3 : HCl
Mol.Wt.: 379.5 : 36.5
Inv. Status: In Stock

Donepezil Impurity 17

Picture of Donepezil Impurity 17
SZ CAT No:: SZ-D003046
CAS No: 171723-80-1
Mol.F.: C25H26N2O2
Mol.Wt.: 386.5
Inv. Status: In Stock
Rel. CAS No: 171722-90-0 (HCl salt)

Donepezil Impurity 2

Picture of Donepezil Impurity 2
SZ CAT No:: SZ-D003028
CAS No: 36517-91-6
Mol.F.: C11H10O4 
Mol.Wt.: 206.2
Inv. Status: In Stock

Donepezil Impurity 28

Picture of Donepezil Impurity 28
SZ CAT No:: SZ-D003064
CAS No: NA
Mol.F.: C17H23NO3 : C20H18O10
Mol.Wt.: 289.4 : 418.4
Inv. Status: In Stock

Donepezil N-Oxide

Picture of Donepezil N-Oxide
SZ CAT No:: SZ-D003011
CAS No: 120013-84-5
Mol.F.: C24H29NO4
Mol.Wt.: 395.5
Inv. Status: In Stock

Donepezil Open Ring Impurity (sodium salt) (USP)

Picture of Donepezil Open Ring Impurity (sodium salt) (USP)
SZ CAT No:: SZ-D003026
CAS No: NA
Mol.F.: C24H28NO5 : Na
Mol.Wt.: 410.5 : 23.0
Inv. Status: In Stock
Rel. CAS No: 197010-25-6 (free base) ; 2217617-87-1 (HCl salt)
Rel. CAT No: SZ-D003059 ,

Donepezil Pyridine Dehydro Impurity

Picture of Donepezil Pyridine Dehydro Impurity
SZ CAT No:: SZ-D003025
CAS No: 4803-74-1
Mol.F.: C17H15NO3
Mol.Wt.: 281.3
Inv. Status: In Stock

Donepezil Pyridine Dehydro N-Oxide

Picture of Donepezil Pyridine Dehydro N-Oxide
SZ CAT No:: SZ-D003019
CAS No: 896134-06-8
Mol.F.: C17H15NO4 
Mol.Wt.: 297.3
Inv. Status: In Stock

Donepezil 3-Hydroxy Impurity (Mixture of diastereomers)

Picture of Donepezil 3-Hydroxy Impurity (Mixture of diastereomers)
SZ CAT No:: SZ-D003023
CAS No: 2097683-67-3
Mol.F.: C24H29NO4 
Mol.Wt.: 395.5
Inv. Status: In Stock

Donepezil 6-O-Desmethyl Impurity

Picture of Donepezil 6-O-Desmethyl Impurity
SZ CAT No:: SZ-D003017
CAS No: 120013-56-1
Mol.F.: C23H27NO3
Mol.Wt.: 365.5
Inv. Status: In Stock

Donepezil Pyridine N-Oxide

Picture of Donepezil Pyridine N-Oxide
SZ CAT No:: SZ-D003020
CAS No: 896134-07-9
Mol.F.: C17H17NO4 
Mol.Wt.: 299.3
Inv. Status: In Stock

Hydroxy Donepezil (Mixture of diastereomers)

Picture of Hydroxy Donepezil (Mixture of diastereomers)
SZ CAT No:: SZ-D003004
CAS No: 197010-20-1
Mol.F.: C24H29NO4
Mol.Wt.: 395.5
Inv. Status: In Stock

3-keto 2-ene Donepezil

Picture of 3-keto 2-ene Donepezil
SZ CAT No:: SZ-D003037
CAS No: NA
Mol.F.: C24H25NO4
Mol.Wt.: 391.5
Inv. Status: Out of Stock

Donepezil O-Benzyl Enol Ether

Picture of Donepezil O-Benzyl Enol Ether
SZ CAT No:: SZ-D003032
CAS No: NA
Mol.F.: C31H35NO3
Mol.Wt.: 469.6
Inv. Status: Out of Stock

6-O-Desmethyl Donepezil Glucuronide (Mixture of Diastereomers)

Picture of 6-O-Desmethyl Donepezil Glucuronide (Mixture of Diastereomers)
SZ CAT No:: SZ-D003054
CAS No: 220170-73-0
Mol.F.: C29H35NO9
Mol.Wt.: 541.6
Inv. Status: Custom Synthesis

Donepezil Alkene Pyridine N-Oxide

Picture of Donepezil Alkene Pyridine N-Oxide
SZ CAT No:: SZ-D003027
CAS No: 2452407-68-8
Mol.F.: C17H151NO4 
Mol.Wt.: 297.3
Inv. Status: Custom Synthesis

Donepezil Didesmethyl Impurity

Picture of Donepezil Didesmethyl Impurity
SZ CAT No:: SZ-D003018
CAS No: 220170-71-8
Mol.F.: C22H25NO3 
Mol.Wt.: 351.4
Inv. Status: Custom Synthesis

Donepezil EP Impurity C

Picture of Donepezil EP Impurity C
SZ CAT No:: SZ-D003038
CAS No: NA
Mol.F.: C24H29NO4
Mol.Wt.: 395.5
Inv. Status: Custom Synthesis

Donepezil EP Impurity F (Z Isomer)

Picture of Donepezil EP Impurity F (Z Isomer)
SZ CAT No:: SZ-D003063
CAS No: 1563189-65-0
Mol.F.: C24H27NO3
Mol.Wt.: 377.5
Inv. Status: Custom Synthesis

Donepezil EP Impurity G

Picture of Donepezil EP Impurity G
SZ CAT No:: SZ-D003039
CAS No: 2452407-72-4
Mol.F.: C24H27NO3
Mol.Wt.: 377.5
Inv. Status: Custom Synthesis

Donepezil Hydrochloride Monohydrate

Picture of Donepezil Hydrochloride Monohydrate
SZ CAT No:: SZ-D003052
CAS No: 884740-09-4
Mol.F.: C24H29NO3 : HCl : H2O
Mol.Wt.: 379.5 : 36.5 : 18.0
Inv. Status: Custom Synthesis
Rel. CAS No: 120014-06-4 (free base) ; 120011-70-3 (HCl salt) ; 794512-61-1 (HBr salt)

Donepezil Hydroxy Acid Impurity

Picture of Donepezil Hydroxy Acid Impurity
SZ CAT No:: SZ-D003015
CAS No: NA
Mol.F.: C24H31NO5
Mol.Wt.: 413.5
Inv. Status: Custom Synthesis

Donepezil Impurity 11

Picture of Donepezil Impurity 11
SZ CAT No:: SZ-D003036
CAS No: 2230493-73-7
Mol.F.: C24H27NO3 
Mol.Wt.: 377.5
Inv. Status: Custom Synthesis

Donepezil Impurity 14

Picture of Donepezil Impurity 14
SZ CAT No:: SZ-D003042
CAS No: 329010-67-5
Mol.F.: C24H29NO4
Mol.Wt.: 395.5
Inv. Status: Custom Synthesis

Donepezil Impurity 15

Picture of Donepezil Impurity 15
SZ CAT No:: SZ-D003043
CAS No: NA
Mol.F.: C17H23NO3
Mol.Wt.: 289.4
Inv. Status: Custom Synthesis

Donepezil Impurity 16

Picture of Donepezil Impurity 16
SZ CAT No:: SZ-D003044
CAS No: 1034439-43-4
Mol.F.: C17H25NO2 : HCl
Mol.Wt.: 275.4 : 36.5
Inv. Status: Custom Synthesis
Rel. CAS No: 844694-83-3 (free base)

Donepezil Impurity 18

Picture of Donepezil Impurity 18
SZ CAT No:: SZ-D003047
CAS No: 110406-97-8
Mol.F.: C11H15ClO2
Mol.Wt.: 214.7
Inv. Status: Custom Synthesis

Donepezil Impurity 19

Picture of Donepezil Impurity 19
SZ CAT No:: SZ-D003048
CAS No: 50786-50-0
Mol.F.: C11H15ClO3
Mol.Wt.: 230.7
Inv. Status: Custom Synthesis

Donepezil Impurity 21

Picture of Donepezil Impurity 21
SZ CAT No:: SZ-D003051
CAS No: 4693-38-3
Mol.F.: C11H13ClO3
Mol.Wt.: 228.7
Inv. Status: Custom Synthesis

Donepezil Impurity 22

Picture of Donepezil Impurity 22
SZ CAT No:: SZ-D003053
CAS No: NA
Mol.F.: C18H17NO3
Mol.Wt.: 295.3
Inv. Status: Custom Synthesis

Donepezil Impurity 23

Picture of Donepezil Impurity 23
SZ CAT No:: SZ-D003055
CAS No: 67686-01-5
Mol.F.: C13H19NO
Mol.Wt.: 205.3
Inv. Status: Custom Synthesis
Rel. CAS No: 121183-26-4 (HCl salt)

Donepezil Impurity 24

Picture of Donepezil Impurity 24
SZ CAT No:: SZ-D003056
CAS No: 2905-56-8
Mol.F.: C12H17N
Mol.Wt.: 175.3
Inv. Status: Custom Synthesis

Donepezil Impurity 25

Picture of Donepezil Impurity 25
SZ CAT No:: SZ-D003057
CAS No: 24228-40-8
Mol.F.: C15H21NO2
Mol.Wt.: 247.3
Inv. Status: Custom Synthesis
Rel. CAS No: 111627-24-8 (HCl salt)

Donepezil Impurity 26

Picture of Donepezil Impurity 26
SZ CAT No:: SZ-D003058
CAS No: NA
Mol.F.: C17H28N2
Mol.Wt.: 260.4
Inv. Status: Custom Synthesis

Donepezil Impurity 27

Picture of Donepezil Impurity 27
SZ CAT No:: SZ-D003061
CAS No: 923571-15-7
Mol.F.: C17H15NO4
Mol.Wt.: 297.3
Inv. Status: Custom Synthesis

Donepezil Impurity 4

Picture of Donepezil Impurity 4
SZ CAT No:: SZ-D003030
CAS No: 2452407-69-9
Mol.F.: C24H29NO3 
Mol.Wt.: 379.5
Inv. Status: Custom Synthesis

Donepezil Impurity 8

Picture of Donepezil Impurity 8
SZ CAT No:: SZ-D003033
CAS No: 1808997-65-0
Mol.F.: C18H23NO4 
Mol.Wt.: 317.4
Inv. Status: Custom Synthesis

Donepezil Impurity 9

Picture of Donepezil Impurity 9
SZ CAT No:: SZ-D003034
CAS No: 2452407-71-3
Mol.F.: C26H33NO4 
Mol.Wt.: 423.6
Inv. Status: Custom Synthesis

Donepezil Open Ring (USP)

Picture of Donepezil Open Ring (USP)
SZ CAT No:: SZ-D003059
CAS No: 197010-25-6
Mol.F.: C24H29NO5
Mol.Wt.: 411.5
Inv. Status: Custom Synthesis
Rel. CAS No: 2217617-87-1 (HCl salt)
Rel. CAT No: SZ-D003026 ,

Donepezil 4-Hydroxy Impurity

Picture of Donepezil 4-Hydroxy Impurity
SZ CAT No:: SZ-D003021
CAS No: 197010-22-3
Mol.F.: C24H29NO4 
Mol.Wt.: 395.5
Inv. Status: Custom Synthesis

Donepezil 5-O-Desmethyl Impurity

Picture of Donepezil 5-O-Desmethyl Impurity
SZ CAT No:: SZ-D003022
CAS No: 120013-57-2
Mol.F.: C23H27NO3 
Mol.Wt.: 365.5
Inv. Status: Custom Synthesis

(R)-Donepezil

Picture of (R)-Donepezil
SZ CAT No:: SZ-D003062
CAS No: 142698-19-9
Mol.F.: C24H29NO3
Mol.Wt.: 379.5
Inv. Status: Under Synthesis

Stable Isotopes And Metabolites

Donepezil D7

Picture of Donepezil D7
SZ CAT No:: SZ-D003D05
CAS No: 1215071-00-3
Mol.F.: C24H22D7NO3
Mol.Wt.: 386.5
Inv. Status: In Stock

6-O-Desmethyl Donepezil D5

Picture of 6-O-Desmethyl Donepezil D5
SZ CAT No:: SZ-D003D06
CAS No: 1189443-74-0
Mol.F.: C23H22D5NO3
Mol.Wt.: 370.5
Inv. Status: Custom Synthesis

Donepezil D6

Picture of Donepezil D6
SZ CAT No:: SZ-D003D04
CAS No: 1207959-41-8
Mol.F.: C24H23D6NO3
Mol.Wt.: 385.5
Inv. Status: Custom Synthesis

Donepezil N-Oxide D6

Picture of Donepezil N-Oxide D6
SZ CAT No:: SZ-D003D07
CAS No: NA
Mol.F.: C24H23D6NO4
Mol.Wt.: 401.5
Inv. Status: Custom Synthesis

Donepezil N-Oxide D7

Picture of Donepezil N-Oxide D7
SZ CAT No:: SZ-D003D08
CAS No: NA
Mol.F.: C24H22D7NO4
Mol.Wt.: 402.5
Inv. Status: Custom Synthesis

Donepezil-d4

Picture of Donepezil-d4
SZ CAT No:: SZ-D003D02
CAS No: 1219908-72-1
Mol.F.: C24H25D4NO3
Mol.Wt.: 383.5
Inv. Status: Custom Synthesis

Donepezil-d5

Picture of Donepezil-d5
SZ CAT No:: SZ-D003D03
CAS No: 1128086-25-8
Mol.F.: C24H24D5NO3
Mol.Wt.: 384.5
Inv. Status: Custom Synthesis

Possible Nitroso Standards

N-Nitroso Donepezil EP Impurity A

Picture of N-Nitroso Donepezil EP Impurity A
SZ CAT No:: SZ-D003050
CAS No: NA
Mol.F.: C17H22N2O4
Mol.Wt.: 318.4
Inv. Status: In Stock

Donepezil 2-Ethylbutyl Nitroso Impurity

Picture of Donepezil 2-Ethylbutyl Nitroso Impurity
SZ CAT No:: SZ-D003060
CAS No: NA
Mol.F.: C24H30N2O4
Mol.Wt.: 410.5
Inv. Status: Custom Synthesis

Donepezil Nitroso Impurity 1

Picture of Donepezil Nitroso Impurity 1
SZ CAT No:: SZ-D003065
CAS No: NA
Mol.F.: C17H24N2O4
Mol.Wt.: 320.4
Inv. Status:
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