Donepezil Impurity 16

SZ CAT No:	SZ-D003044
CAS No	1034439-43-4
Mol.F.	C17H25NO2 : HCl
Mol.Wt.	275.4 : 36.5
Inv. Status	Custom Synthesis
Rel. CAS No	844694-83-3 (free base)

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Chemical Name: 5,6-Dimethoxy-2-[(4-piperidyl)methyl]indane hydrochloride

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: COC1=CC2=C(C=C1OC)CC(CC3CCNCC3)C2.Cl

New gradient high-performance liquid chromatography method for determination of donepezil hydrochloride assay and impurities content in oral pharmaceutical formulation
Stella Kafkala ∗, Stella Matthaiou, Pandora Alexaki, Morfis Abatzis, Antonios Bartzeliotis, Maria Katsiabani
Journal of Chromatography A, 1189 (2008) 392–397

Identification and characterization of potential impurities of donepezil
K.V.S.R. Krishna Reddy a, J. Moses Babu a, P. Anil Kumar b, E.R.R. Chandrashekar b, Vijayavitthal T. Mathad b, S. Eswaraiah b, M. Satyanarayana Reddy b, K. Vyas
Journal of Pharmaceutical and Biomedical Analysis 35 (2004) 1047–1058

An Improved and Efficient Process for the Production of Donepezil Hydrochloride: Substitution of Sodium Hydroxide for n-Butyl Lithium via Phase Transfer Catalysis
Navanath Niphade, Anil Mali, Kunal Jagtap, Ramesh Chandra Ojha, Pravinchandra J. Vankawala, and Vijayavitthal T. Mathad
Organic Process Research & Development 2008, 12, 731–735

Analytical Method Development and Validation for the Analysis of Donepezil Hydrochloride and Its Related Substances Using Ultra Perfomance Liquid Chromatography
Mahalingam V* , Kalaivani R A, Somanathan T, Vijayabaskar S
International Journal of Pharmaceutical and Clinical Research 2017; 9(5): 417-424

Donepezil Impurity 16 is chemically 5,6-Dimethoxy-2-[(4-piperidyl)methyl]indane hydrochloride. Donepezil Impurity 16 is supplied with detailed characterization data compliant with regulatory guideline. Donepezil Impurity 16 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Donepezil.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Donepezil Impurity 16

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SZ CAT No:	: SZ-D003D06
CAS No	: 1189443-74-0
Mol.F.	: C23H22D5NO3
Mol.Wt.	: 370.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-D003054
CAS No	: 220170-73-0
Mol.F.	: C29H35NO9
Mol.Wt.	: 541.6
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-D003007
CAS No	: 120013-45-8
Mol.F.	: C24H29NO2
Mol.Wt.	: 363.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-D003008
CAS No	: 1034439-57-0
Mol.F.	: C24H31NO2 : HCl
Mol.Wt.	: 365.5 : 36.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-D003040
CAS No	: 120014-06-4
Mol.F.	: C24H29NO3
Mol.Wt.	: 379.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-D003014
CAS No	: 22065-85-6
Mol.F.	: C13H17NO
Mol.Wt.	: 203.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-D003019
CAS No	: 896134-06-8
Mol.F.	: C17H15NO4
Mol.Wt.	: 297.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-D003027
CAS No	: 2452407-68-8
Mol.F.	: C17H151NO4
Mol.Wt.	: 297.3
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-D003006
CAS No	: 844694-85-5
Mol.F.	: C31H36NO3 : Br
Mol.Wt.	: 470.6 : 79.9
Inv. Status	: In Stock

SZ CAT No:	: SZ-D003D04
CAS No	: 1207959-41-8
Mol.F.	: C24H23D6NO3
Mol.Wt.	: 385.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-D003D05
CAS No	: 1215071-00-3
Mol.F.	: C24H22D7NO3
Mol.Wt.	: 386.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-D003018
CAS No	: 220170-71-8
Mol.F.	: C22H25NO3
Mol.Wt.	: 351.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-D003016
CAS No	: 120012-04-6
Mol.F.	: C24H31NO3
Mol.Wt.	: 381.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-D003009
CAS No	: 120014-30-4
Mol.F.	: C17H23NO3
Mol.Wt.	: 289.4
Inv. Status	: Out of Stock, Custom Synthesis

SZ CAT No:	: SZ-D003045
CAS No	: 120013-39-0
Mol.F.	: C17H23NO3 : HCl
Mol.Wt.	: 289.4 : 36.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-D003024
CAS No	: 2107-69-9
Mol.F.	: C11H12O3
Mol.Wt.	: 192.2
Inv. Status	: In Stock

SZ CAT No:	: SZ-D003038
CAS No	: NA
Mol.F.	: C24H29NO4
Mol.Wt.	: 395.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-D003013
CAS No	: 4803-57-0
Mol.F.	: C17H17NO3
Mol.Wt.	: 283.3
Inv. Status	: In Stock

SZ CAT No:	: SZ-D003031
CAS No	: 231283-82-2
Mol.F.	: C24H24NO3 : Br
Mol.Wt.	: 374.5 : 79.9
Inv. Status	: In Stock

SZ CAT No:	: SZ-D003002
CAS No	: 145546-80-1
Mol.F.	: C24H27NO3
Mol.Wt.	: 377.5
Inv. Status	: In Stock

Donepezil Impurity 16

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SZ CAT No:	: SZ-D003039
CAS No	: 2452407-72-4
Mol.F.	: C24H27NO3
Mol.Wt.	: 377.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-D003001
CAS No	: 120011-70-3
Mol.F.	: C24H29NO3 : HCl
Mol.Wt.	: 379.5 : 36.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-D003052
CAS No	: 884740-09-4
Mol.F.	: C24H29NO3 : HCl : H2O
Mol.Wt.	: 379.5 : 36.5 : 18.0
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-D003015
CAS No	: NA
Mol.F.	: C24H31NO5
Mol.Wt.	: 413.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-D003036
CAS No	: 2230493-73-7
Mol.F.	: C24H27NO3
Mol.Wt.	: 377.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-D003037
CAS No	: NA
Mol.F.	: C24H25NO4
Mol.Wt.	: 391.5
Inv. Status	: Out of Stock

SZ CAT No:	: SZ-D003041
CAS No	: 608511-44-0
Mol.F.	: C24H27NO3
Mol.Wt.	: 377.5
Inv. Status	: In Stock

SZ CAT No:	: SZ-D003042
CAS No	: 329010-67-5
Mol.F.	: C24H29NO4
Mol.Wt.	: 395.5
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-D003043
CAS No	: NA
Mol.F.	: C17H23NO3
Mol.Wt.	: 289.4
Inv. Status	: Custom Synthesis

SZ CAT No:	: SZ-D003044
CAS No	: 1034439-43-4
Mol.F.	: C17H25NO2 : HCl
Mol.Wt.	: 275.4 : 36.5
Inv. Status	: Custom Synthesis