Afatinib Impurity B

SZ CAT No:	SZ-A054003
CAS No	314771-76-1
Mol.F.	C18H16ClFN4O2
Mol.Wt.	374.8
Inv. Status	In Stock
Rel. CAS No	2047333-82-2 (HCl salt)

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Chemical Name: N4-(3-Chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4,6-quinazolinediamine

Synonym: Afatinib Diamine Impurity

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: ClC1=C(F)C=CC(NC2=NC=NC3=C2C=C(N)C(O[C@H]4CCOC4)=C3)=C1

Afatinib Impurity B is chemically N4-(3-Chloro-4-fluorophenyl)-7-[[(3S)-tetrahydro-3-furanyl]oxy]-4,6-quinazolinediamine. It is also known as Afatinib Diamine Impurity. Afatinib Impurity B is supplied with detailed characterization data compliant with regulatory guideline. Afatinib Impurity B can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Afatinib.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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Afatinib Impurity 10

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Afatinib Impurity 11

SZ CAT No:	: SZ-A054023
CAS No	: 2413212-17-4
Mol.F.	: C22H20ClFN4O3
Mol.Wt.	: 442.9
Inv. Status	: Custom Synthesis

Afatinib Impurity 12

SZ CAT No:	: SZ-A054024
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Mol.F.	: C22H20ClFN4O4
Mol.Wt.	: 458.9
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Afatinib Impurity 13

SZ CAT No:	: SZ-A054025
CAS No	: 2413212-19-6
Mol.F.	: C22H20ClFN4O4
Mol.Wt.	: 458.9
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Afatinib Impurity 14

SZ CAT No:	: SZ-A054026
CAS No	: 2413212-21-0
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Afatinib Impurity 15

SZ CAT No:	: SZ-A054027
CAS No	: 2413212-23-2
Mol.F.	: C24H27ClFN5O4
Mol.Wt.	: 504.0
Inv. Status	: Custom Synthesis

Afatinib Impurity 16

SZ CAT No:	: SZ-A054028
CAS No	: 2223677-60-7
Mol.F.	: C19H16ClFN4O3
Mol.Wt.	: 402.8
Inv. Status	: Under Synthesis

Afatinib Impurity 17

SZ CAT No:	: SZ-A054029
CAS No	: NA
Mol.F.	: C21H22ClFN5O2
Mol.Wt.	: 430.9
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Afatinib Impurity 18

SZ CAT No:	: SZ-A054030
CAS No	: 2413212-25-4
Mol.F.	: C24H26FN5O3
Mol.Wt.	: 451.5
Inv. Status	: Custom Synthesis

Afatinib Impurity 19

SZ CAT No:	: SZ-A054031
CAS No	: 1245555-42-3
Mol.F.	: C21H21ClFN5O2
Mol.Wt.	: 429.9
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Afatinib Impurity 2

SZ CAT No:	: SZ-A054014
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Mol.F.	: C14H8ClFN4O3
Mol.Wt.	: 334.7
Inv. Status	: Custom Synthesis

Afatinib Impurity 20

SZ CAT No:	: SZ-A054032
CAS No	: 2085843-51-0
Mol.F.	: C22H23ClFN5O2
Mol.Wt.	: 443.9
Inv. Status	: In Stock

Afatinib Impurity 21

SZ CAT No:	: SZ-A054033
CAS No	: 2044709-72-8
Mol.F.	: C18H16F2N4O2
Mol.Wt.	: 358.4
Inv. Status	: Custom Synthesis

Afatinib Impurity 22

SZ CAT No:	: SZ-A054034
CAS No	: NA
Mol.F.	: C28H29ClFN5O7
Mol.Wt.	: 601.1
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Afatinib Impurity 40

SZ CAT No:	: SZ-A054041
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Mol.F.	: C20H18ClFN4O3
Mol.Wt.	: 416.8
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Afatinib Impurity 41

SZ CAT No:	: SZ-A054042
CAS No	: 2475095-50-0
Mol.F.	: C14H7ClF2N4O2
Mol.Wt.	: 336.7
Inv. Status	: In Stock

Afatinib Impurity 23

SZ CAT No:	: SZ-A054036
CAS No	: 2223677-58-3
Mol.F.	: C22H20ClFN4O4
Mol.Wt.	: 458.9
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Afatinib Impurity 24

SZ CAT No:	: SZ-A054043
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Afatinib Impurity 25

SZ CAT No:	: SZ-A054044
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SZ CAT No:	: SZ-A054045
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Mol.Wt.	: 404.8
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SZ CAT No:	: SZ-A054046
CAS No	: 618061-76-0
Mol.F.	: C24H27ClFN4O6P
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Afatinib Impurity 28

SZ CAT No:	: SZ-A054047
CAS No	: NA
Mol.F.	: C22H20ClFN4O4
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Afatinib Impurity 29

SZ CAT No:	: SZ-A054048
CAS No	: NA
Mol.F.	: C22H23ClFN4O6P
Mol.Wt.	: 524.9
Inv. Status	: Custom Synthesis

Afatinib Impurity 3

SZ CAT No:	: SZ-A054015
CAS No	: 2475094-96-1
Mol.F.	: C14H7ClF2N4O2
Mol.Wt.	: 336.7
Inv. Status	: Custom Synthesis

Afatinib Impurity 32

SZ CAT No:	: SZ-A054051
CAS No	: 2323570-72-3
Mol.F.	: C24H27ClFN5O4
Mol.Wt.	: 504.0
Inv. Status	: In Stock

Afatinib Impurity 4

SZ CAT No:	: SZ-A054016
CAS No	: 2512206-82-3
Mol.F.	: C14H7Cl2FN4O2
Mol.Wt.	: 353.1
Inv. Status	: In Stock

Afatinib Impurity 5

SZ CAT No:	: SZ-A054017
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Mol.F.	: C15H10ClFN4O3
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Inv. Status	: Custom Synthesis

Afatinib Impurity 6

SZ CAT No:	: SZ-A054018
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Mol.Wt.	: 340.4
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Afatinib Impurity 7

SZ CAT No:	: SZ-A054019
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SZ CAT No:	: SZ-A054020
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Afatinib Impurity A

SZ CAT No:	: SZ-A054002
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SZ CAT No:	: SZ-A054003
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Mol.Wt.	: 374.8
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SZ CAT No:	: SZ-A054004
CAS No	: 945553-91-3
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Mol.Wt.	: 486.0
Inv. Status	: In Stock

Afatinib Impurity D

SZ CAT No:	: SZ-A054005
CAS No	: 1680184-59-1
Mol.F.	: C24H25ClFN5O3
Mol.Wt.	: 485.9
Inv. Status	: Limited Stock

Afatinib Impurity E

SZ CAT No:	: SZ-A054006
CAS No	: 2223677-63-0
Mol.F.	: C24H25Cl2N5O3
Mol.Wt.	: 502.4
Inv. Status	: Custom Synthesis

Afatinib Impurity F

SZ CAT No:	: SZ-A054007
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Mol.F.	: C24H25F2N5O3
Mol.Wt.	: 469.5
Inv. Status	: Custom Synthesis

Afatinib Impurity G

SZ CAT No:	: SZ-A054008
CAS No	: NA
Mol.F.	: C24H25ClFN5O3
Mol.Wt.	: 486.0
Inv. Status	: Custom Synthesis

Afatinib Impurity I

SZ CAT No:	: SZ-A054010
CAS No	: NA
Mol.F.	: C22H19BrClFN4O3
Mol.Wt.	: 521.8
Inv. Status	: Custom Synthesis

Afatinib Impurity J

SZ CAT No:	: SZ-A054011
CAS No	: 1456696-14-2
Mol.F.	: C18H22N4O4
Mol.Wt.	: 358.4
Inv. Status	: Custom Synthesis

Afatinib Nitroso Impurity 1

SZ CAT No:	: SZ-A054040
CAS No	: NA
Mol.F.	: C24H24ClFN6O4
Mol.Wt.	: 514.9
Inv. Status	: Inquire

Afatinib N-Oxide

SZ CAT No:	: SZ-A054013
CAS No	: 2413212-11-8
Mol.F.	: C24H25ClFN5O4
Mol.Wt.	: 501.9
Inv. Status	: In Stock

Afatinib Sulfonic Acid Analog

SZ CAT No:	: SZ-A054037
CAS No	: 2283295-16-7
Mol.F.	: C24H27ClFN5O6S
Mol.Wt.	: 568.0
Inv. Status	: Custom Synthesis

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SZ CAT No:	: SZ-A054012
CAS No	: 2413212-13-0
Mol.F.	: C23H23ClFN5O3
Mol.Wt.	: 471.9
Inv. Status	: Custom Synthesis

Afatinib Impurity B

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