Afatinib Impurity 12

SZ CAT No:	SZ-A054024
CAS No	2121530-37-6
Mol.F.	C22H20ClFN4O4
Mol.Wt.	458.9
Inv. Status	Custom Synthesis

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Chemical Name: (S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-hydroxybut-2-enamide

Synonym: 4-Hydroxy 4-Dedimethylamino Afatinib

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: FC(C=C1)=C(Cl)C=C1NC2=NC=NC3=CC(O[C@H]4CCOC4)=C(NC(/C=C/CO)=O)C=C32

Afatinib Impurity 12 is chemically (S,E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-((tetrahydrofuran-3-yl)oxy)quinazolin-6-yl)-4-hydroxybut-2-enamide. It is also known as 4-Hydroxy 4-Dedimethylamino Afatinib. Afatinib Impurity 12 is supplied with detailed characterization data compliant with regulatory guideline. Afatinib Impurity 12 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Afatinib.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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Afatinib Impurity 10

SZ CAT No:	: SZ-A054022
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Afatinib Impurity 11

SZ CAT No:	: SZ-A054023
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SZ CAT No:	: SZ-A054025
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Mol.F.	: C22H20ClFN4O4
Mol.Wt.	: 458.9
Inv. Status	: In Stock

Afatinib Impurity 14

SZ CAT No:	: SZ-A054026
CAS No	: 2413212-21-0
Mol.F.	: C24H27ClFN5O4
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Inv. Status	: Custom Synthesis

Afatinib Impurity 15

SZ CAT No:	: SZ-A054027
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Afatinib Impurity 16

SZ CAT No:	: SZ-A054028
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Mol.F.	: C19H16ClFN4O3
Mol.Wt.	: 402.8
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Afatinib Impurity 17

SZ CAT No:	: SZ-A054029
CAS No	: NA
Mol.F.	: C21H22ClFN5O2
Mol.Wt.	: 430.9
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Afatinib Impurity 18

SZ CAT No:	: SZ-A054030
CAS No	: 2413212-25-4
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Afatinib Impurity 19

SZ CAT No:	: SZ-A054031
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Afatinib Impurity 2

SZ CAT No:	: SZ-A054014
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Mol.F.	: C14H8ClFN4O3
Mol.Wt.	: 334.7
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Afatinib Impurity 20

SZ CAT No:	: SZ-A054032
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Mol.F.	: C22H23ClFN5O2
Mol.Wt.	: 443.9
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Afatinib Impurity 21

SZ CAT No:	: SZ-A054033
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Afatinib Impurity 22

SZ CAT No:	: SZ-A054034
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Mol.F.	: C28H29ClFN5O7
Mol.Wt.	: 601.1
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Afatinib Impurity 40

SZ CAT No:	: SZ-A054041
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Mol.F.	: C20H18ClFN4O3
Mol.Wt.	: 416.8
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Afatinib Impurity 41

SZ CAT No:	: SZ-A054042
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SZ CAT No:	: SZ-A054044
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SZ CAT No:	: SZ-A054045
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SZ CAT No:	: SZ-A054046
CAS No	: 618061-76-0
Mol.F.	: C24H27ClFN4O6P
Mol.Wt.	: 552.9
Inv. Status	: In Stock

Afatinib Impurity 28

SZ CAT No:	: SZ-A054047
CAS No	: NA
Mol.F.	: C22H20ClFN4O4
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Afatinib Impurity 29

SZ CAT No:	: SZ-A054048
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SZ CAT No:	: SZ-A054002
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SZ CAT No:	: SZ-A054003
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SZ CAT No:	: SZ-A054004
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SZ CAT No:	: SZ-A054005
CAS No	: 1680184-59-1
Mol.F.	: C24H25ClFN5O3
Mol.Wt.	: 485.9
Inv. Status	: Limited Stock

Afatinib Impurity E

SZ CAT No:	: SZ-A054006
CAS No	: 2223677-63-0
Mol.F.	: C24H25Cl2N5O3
Mol.Wt.	: 502.4
Inv. Status	: Custom Synthesis

Afatinib Impurity F

SZ CAT No:	: SZ-A054007
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Mol.F.	: C24H25F2N5O3
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Inv. Status	: Custom Synthesis

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SZ CAT No:	: SZ-A054008
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Mol.F.	: C24H25ClFN5O3
Mol.Wt.	: 486.0
Inv. Status	: Custom Synthesis

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SZ CAT No:	: SZ-A054010
CAS No	: NA
Mol.F.	: C22H19BrClFN4O3
Mol.Wt.	: 521.8
Inv. Status	: Custom Synthesis

Afatinib Impurity J

SZ CAT No:	: SZ-A054011
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Inv. Status	: Custom Synthesis

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SZ CAT No:	: SZ-A054040
CAS No	: NA
Mol.F.	: C24H24ClFN6O4
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SZ CAT No:	: SZ-A054013
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Mol.F.	: C24H25ClFN5O4
Mol.Wt.	: 501.9
Inv. Status	: In Stock

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SZ CAT No:	: SZ-A054037
CAS No	: 2283295-16-7
Mol.F.	: C24H27ClFN5O6S
Mol.Wt.	: 568.0
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SZ CAT No:	: SZ-A054012
CAS No	: 2413212-13-0
Mol.F.	: C23H23ClFN5O3
Mol.Wt.	: 471.9
Inv. Status	: Custom Synthesis

Afatinib Impurity 12

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