Methotrexate 7-Hydroxy Metabolite

N° de SZ CAT:	SZ-M019014
Número CAS	5939-37-7
Mol.F.	C20H22N8O6
Peso Molecular	470.4
Status de Fatura	Limited Stock

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Nome Químico: 4-Amino-7-hydroxy-10-methylpteroylglutamic acid ; (4-(((2,4-diamino-7-hydroxypteridin-6-yl)methyl)(methyl)amino)benzoyl)-L-glutamic acid

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Sorrisos: CN(C1=CC=C(C(N[C@H](C(O)=O)CCC(O)=O)=O)C=C1)CC2=NC3=C(N)N=C(N)N=C3N=C2O

Identification and Quantitation of Impurities in Methotrexate
dulal c. chatterji, altice g. frazier, and joseph f. gallell
Journal of Pharmaceutical Sciences Volume 67, Issue 5, May 1978, Pages 622-624

determination of methotrexate and its major metabolite, 7_hydroxymethotrexate, using capillary zone electrophoresis and laser-induced fluorescence detection
mark c. roach, philippe gozel and richard n. zare
Journal of Chromatography, 426 (1988) 129-140

Analytical methodologies for determination of methotrexate and its metabolites in pharmaceutical, biological and environmental samples
Forough Karami , Sara Ranjbar , Younes Ghasemi , Manica Negahdaripour
Journal of Pharmaceutical Analysis 9 (2019) 373-391

Perspectives of Methotrexate-Based Radioagents for Application in Nuclear Medicine
Paweł Krzysztof Halik,* Przemysław Kozmin ́ ski, and Ewa Gniazdowska
Mol. Pharmaceutics 2021, 18, 1, 33–43

Methotrexate 7-Hydroxy Metabolite is chemically 4-Amino-7-hydroxy-10-methylpteroylglutamic acid ; (4-(((2,4-diamino-7-hydroxypteridin-6-yl)methyl)(methyl)amino)benzoyl)-L-glutamic acid. Methotrexate 7-Hydroxy Metabolite is supplied with detailed characterization data compliant with regulatory guideline. Methotrexate 7-Hydroxy Metabolite can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Methotrexate.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Methotrexate 7-Hydroxy Metabolite

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N° de SZ CAT:	: SZ-M019005
Número CAS	: 5623-18-7
Mol.F.	: C15H14N6O3
Peso Molecular	: 326.3
Status de Fatura	: In Stock

N° de SZ CAT:	: SZ-M019001
Número CAS	: 1212284-68-8
Mol.F.	: C20H22N8O5 : 2(H2O)
Peso Molecular	: 454.4 : 2(18.0)
Status de Fatura	: In Stock

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Número CAS	: 945-24-4
Mol.F.	: C7H8N6O
Peso Molecular	: 192.1
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Mol.F.	: C19H20N8O5 : H2O
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Peso Molecular	: 325.3
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Peso Molecular	: 454.4
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N° de SZ CAT:	: SZ-M019014
Número CAS	: 5939-37-7
Mol.F.	: C20H22N8O6
Peso Molecular	: 470.4
Status de Fatura	: Limited Stock

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Status de Fatura	: Custom Synthesis

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Status de Fatura	: Custom Synthesis

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Status de Fatura	: In Stock

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Mol.F.	: C20H22N8O5
Peso Molecular	: 454.4
Status de Fatura	: Custom Synthesis