Montelukast Ketocarbinol Impurity

SZ CAT No:	SZ-M031031
CAS No	2682015-83-2
Mol.F.	C34H32ClNO4S
Mol.Wt.	586.1
Inv. Status	Custom Synthesis

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Chemical Name: 1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl) ethenyl] phenyl]-3-[2-(1-oxo-2-hydroxyethyl) phenyl] propyl] thio] methyl] cyclopropaneacetic acid

Synonym: Montelukast Ketocarbinol Impurity ; Montelukast Hydroxymethylcarbonyl Analog

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C(C1=CC=CC=C1CC[C@@H](SCC2(CC2)CC(O)=O)C3=CC=CC(/C=C/C4=NC5=CC(Cl)=CC=C5C=C4)=C3)CO

Method development and validation for the simultaneous estimation of montelukast and acebrophylline in bulk and tablet dosage forms by RP-HPLC
By Ankitha, M.; Ashitha, S.; Sri, Ragasudha A.; Latha, Madhavi P. V.; Devi, Uma P.
From Journal of Global Trends in Pharmaceutical Sciences (2021), 12(1), 9173-9179

Montelukast microsuspension with hypromellose for improved stability and oral absorption
By Lee, Ha Ryeong; Park, Hyun Jin; Park, Jun Soo; Park, Dong Woo; Ho, Myoung Jin; Kim, Dong Yoon; Lee, Hyo Chun; Kim, Eun Jeong; Song, Woo Heon; Park, Jun Sang; et al
From International Journal of Biological Macromolecules (2021), 183, 1732-1742

Analytical method development and validation for simultaneous estimation of Bilastine and Montelukast sodium by UV spectrophotometry
By Raj, R. Mohan; Sankar, A. S. K.; Vetrichelvan, T.
From World Journal of Pharmacy and Pharmaceutical Sciences (2021), 10(1), 680-687

Montelukast Ketocarbinol Impurity is chemically 1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl) ethenyl] phenyl]-3-[2-(1-oxo-2-hydroxyethyl) phenyl] propyl] thio] methyl] cyclopropaneacetic acid. It is also known as Montelukast Ketocarbinol Impurity ; Montelukast Hydroxymethylcarbonyl Analog . Montelukast Ketocarbinol Impurity is supplied with detailed characterization data compliant with regulatory guideline. Montelukast Ketocarbinol Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Montelukast.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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