Hydroxychloroquine EP Impurity C (2HCl salt)

Identification and characterization of process related impurities in chloroquine and hydroxychloroquine by LC​/IT​/MS, LC​/TOF​/MS and NMR
By Dongre, Vaijanath G.; Ghugare, Pradeep D.; Karmuse, Pravin; Singh, Dharmendra; Jadhav, Atul; Kumar, Ashok
From Journal of Pharmaceutical and Biomedical Analysis (2009), 49(4), 873-879
 
Analytical and semi-​preparative high-​performance liquid chromatographic separation and assay of hydroxychloroquine enantiomers
By Brocks, Dion R.; Pasutto, Franco M.; Jamali, Fakhreddin
From Journal of Chromatography, Biomedical Applications (1992), 581(1), 83-92
 
Estimation of plasma hydroxychloroquine by high-​performance liquid chromatography with ultraviolet detection
By Morris, Raymond G.
From Journal of Chromatography, Biomedical Applications (1985), 338(2), 422-7
 

Hydroxychloroquine EP Impurity C (2HCl salt) is chemically 2-[[(4RS)-4-[(7-chloroquinolin-4-yl)amino]pentyl]amino]ethan-1-ol Dihydrochloride (as per EP)2-({4-[(7-Chloroquinolin-4-yl)amino]pentyl}amino)ethan-1-ol Dihydrochloride (as per USP). It is also known as Desethylhydroxychloroquine. Hydroxychloroquine EP Impurity C (2HCl salt) is supplied with detailed characterization data compliant with regulatory guideline. Hydroxychloroquine EP Impurity C (2HCl salt) can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Hydroxychloroquine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.