Hydroxychloroquine-d4 O-Sulfate

SZ CAT No:	SZ-H004D03
CAS No	2714483-73-3
Mol.F.	C18H22D4ClN3O4S
Mol.Wt.	420
Inv. Status	Custom Synthesis
Rel. CAS No	103152-84-7 (Unlabelled)

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Chemical Name: 2-((4-((7-Chloroquinolin-4-yl)amino)pentyl-2,2,3,3-d4)(ethyl)amino)ethyl hydrogen sulfate

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: ClC(C=C1)=CC2=C1C(NC(C)C([2H])([2H])C([2H])([2H])CN(CC)CCOS(O)(=O)=O)=CC=N2

Identification and characterization of process related impurities in chloroquine and hydroxychloroquine by LC/IT/MS, LC/TOF/MS and NMR
By Dongre, Vaijanath G.; Ghugare, Pradeep D.; Karmuse, Pravin; Singh, Dharmendra; Jadhav, Atul; Kumar, Ashok
From Journal of Pharmaceutical and Biomedical Analysis (2009), 49(4), 873-879

Analytical and semi-preparative high-performance liquid chromatographic separation and assay of hydroxychloroquine enantiomers
By Brocks, Dion R.; Pasutto, Franco M.; Jamali, Fakhreddin
From Journal of Chromatography, Biomedical Applications (1992), 581(1), 83-92

Estimation of plasma hydroxychloroquine by high-performance liquid chromatography with ultraviolet detection
By Morris, Raymond G.
From Journal of Chromatography, Biomedical Applications (1985), 338(2), 422-7

Hydroxychloroquine-d4 O-Sulfate is chemically 2-((4-((7-Chloroquinolin-4-yl)amino)pentyl-2,2,3,3-d4)(ethyl)amino)ethyl hydrogen sulfate. Hydroxychloroquine-d4 O-Sulfate is supplied with detailed characterization data compliant with regulatory guideline. Hydroxychloroquine-d4 O-Sulfate can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Hydroxychloroquine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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Hydroxychloroquine Impurity 2

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Hydroxychloroquine Impurity 3

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Synthetic impurity mixture of HCQS

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