Search Results for " Tacrolimus "
Tacrolimus EP Impurity G
| SZ CAT No: | SZ-T005008 |
| CAS No | 144490-63-1 |
| Mol.F. | C44H69NO12 |
| Mol.Wt. | 804.0 |
| Inv. Status | Custom Synthesis |
Chemical Name: (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19S,26aS)-5,19-Dihydroxy-3-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-3,4,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a- octadecahydro-7H-15,19-epoxypyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone (as per EP); (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19S,26aS)-8-Allyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a,hexadecahydro-5,19-dihydroxy-3-{(E)-2-[1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl}-14,16,dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone (as per USP)
Synonym: Tacrolimus 19-epimer (USP)
Shipping Temperature: Ambient
HSN Code: 38229010
Country of Origin: India
Smiles: CO[C@@H]1[C@]2([H])[C@@H](OC)C[C@@H](C)[C@](O)(O2)C(C(N3CCCC[C@@]3([H])C(O[C@H](/C(C)=C/[C@@H]4CC[C@@H](O)[C@H](OC)C4)[C@H](C)[C@@H](O)CC([C@H](CC=C)/C=C(C)/C[C@H](C)C1)=O)=O)=O)=O
Tacrolimus EP Impurity G is chemically (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19S,26aS)-5,19-Dihydroxy-3-[(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-3,4,5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a- octadecahydro-7H-15,19-epoxypyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone (as per EP); (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19S,26aS)-8-Allyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a,hexadecahydro-5,19-dihydroxy-3-{(E)-2-[1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl}-14,16,dimethoxy-4,10,12,18-tetramethyl-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone (as per USP). It is also known as Tacrolimus 19-epimer (USP). Tacrolimus EP Impurity G is supplied with detailed characterization data compliant with regulatory guideline. Tacrolimus EP Impurity G can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tacrolimus.
The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.
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