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Picture of Tacrolimus Ring-Opening Impurity

Tacrolimus Ring-Opening Impurity

SZ CAT No:SZ-T005007
CAS No1393890-33-9
Mol.F.C44H69NO12
Mol.Wt.804.0
Inv. StatusCustom Synthesis

Chemical Name: (3S,4R,5S,8R,12S,14S,15R,16S,18R,26aS,Z)-8-Allyl-5,15-dihydroxy-3-((E)-1-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl)-14,16-dimethoxy-4,10,12,18-tetramethyl-5,6,11,12,13,14,15,16,17,18,24,25,26,26a-tetradecahydro-3H-pyrido[2,1-c][1]oxa[4]azacyclotricosine-1,7,19,20,21(4H,8H,23H)-pentaone

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: O=C(O[C@@H]([C@@H]([C@H](CC([C@@H](/C=C(C[C@H](C)C1)/C)CC=C)=O)O)C)/C(C)=C/[C@H](CC[C@H]2O)C[C@H]2OC)[C@@](CCCC3)([H])N3C(C(C([C@@H](C[C@]([C@@H]([C@@]1([H])OC)O)([H])OC)C)=O)=O)=O

Tacrolimus Ring-Opening Impurity is chemically (3S,4R,5S,8R,12S,14S,15R,16S,18R,26aS,Z)-8-Allyl-5,15-dihydroxy-3-((E)-1-((1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl)prop-1-en-2-yl)-14,16-dimethoxy-4,10,12,18-tetramethyl-5,6,11,12,13,14,15,16,17,18,24,25,26,26a-tetradecahydro-3H-pyrido[2,1-c][1]oxa[4]azacyclotricosine-1,7,19,20,21(4H,8H,23H)-pentaone. Tacrolimus Ring-Opening Impurity is supplied with detailed characterization data compliant with regulatory guideline. Tacrolimus Ring-Opening Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Tacrolimus.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

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