Quetiapine EP Impurity D (2HCl salt)

SZ CAT No:	SZ-Q001087
CAS No	NA
Mol.F.	C30H24N4S2 : 2(HCl)
Mol.Wt.	504.7 : 2(36.5)
Inv. Status	In Stock
Rel. CAS No	945668-94-0 (free base)

Disclaimer

SynZeal product information given on this website is as per the existing understanding while publishing the details on website. The customer is responsible for assessing the accuracy of the information at the time of actual purchase.

SynZeal will update these details as per new development or finding in product specification without further noticed.

Chemical Name: 11,11′-(Piperazine-1,4-diyl)bis(dibenzo[b,f][1,4]thiazepine) dihydrochloride (as per EP) ; 1,4-Bis(dibenzo[b,f][1,4]thiazepin-11-yl)piperazine dihydrochloride (as per USP)

Synonym: Quetiapine Dimer Impurity ; Quetiapine Bis(dibenzothiazepinyl) piperazine Impurity (USP)

Shipping Temperature: Ambient

HSN Code: 38229010

Country of Origin: India

Smiles: N1(C2=NC3=CC=CC=C3SC4=CC=CC=C24)CCN(C5=NC6=CC=CC=C6SC7=CC=CC=C57)CC1.[2HCl]

Identification and Characterization of Potential Impurities of Quetiapine Fumarate
Elżbieta U. Stolarczyk,Łukasz Kaczmarek,Kamil Eksanow,Marek Kubiszewski,Magdalena Glice &Andrzej Kutner
Pharmaceutical Development and Technology Volume 14, 2009 - Issue 1 Pages 29-39

An Improved and Single Pot Process for the Production of Quetiapine Hemifumarate Substantially Free from Potential Impurities
Navnath C. Niphade, Anil C. Mali, Bhushan S. Pandit, Kunal M. Jagtap, Sanjay A. Jadhav, Madhukar N. Jachak, and Vijayavitthal T. Mathad
Org. Process Res. Dev. 2009, 13, 4, 792–797

Stability indicating fast LC method for determination of quetiapine fumarate related substances in bulk and pharmaceutical formulation
R.Narendra Kumar, *G.Nageswara Rao, P.Y.Naidu
Der Pharmacia Lettre, 2011, 3(3): 457-469

Quetiapine EP Impurity D (2HCl salt) is chemically 11,11′-(Piperazine-1,4-diyl)bis(dibenzo[b,f][1,4]thiazepine) dihydrochloride (as per EP) ; 1,4-Bis(dibenzo[b,f][1,4]thiazepin-11-yl)piperazine dihydrochloride (as per USP). It is also known as Quetiapine Dimer Impurity ; Quetiapine Bis(dibenzothiazepinyl) piperazine Impurity (USP). Quetiapine EP Impurity D (2HCl salt) is supplied with detailed characterization data compliant with regulatory guideline. Quetiapine EP Impurity D (2HCl salt) can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Quetiapine.

The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. SynZeal products are for analytical purpose only and not for human use.

Quetiapine EP Impurity D (2HCl salt)

Contacts

Our Locations